SCHEMBL29428964

SCHEMBL29428964

CSCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.46
SIRT5 Q9NXA8 2/20 0.45
GNPAT O15228 1/20 0.45
FNTA P49354 12/20 0.43
FNTB P49356 12/20 0.43
PGGT1B P53609 10/20 0.43
IL23R Q5VWK5 2/20 0.40
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30463248 1.00 FOLH1 (0.46) FOLH1SIRT5GNPATFNTAFNTB
SCHEMBL30463274 1.00 FOLH1 (0.46) FOLH1SIRT5GNPATFNTAFNTB
SCHEMBL29660264 0.97 GNPAT (0.45) FOLH1SIRT5GNPATFNTAFNTB
SCHEMBL30463272 0.97 FNTA (0.45) FOLH1SIRT5GNPATFNTAFNTB
SCHEMBL31157701 0.95 BACE1 (0.45) FOLH1SIRT5GNPATFNTAFNTB
SCHEMBL31157745 0.95 FOLH1 (0.45) FOLH1SIRT5GNPATFNTAFNTB
SCHEMBL30998021 0.94 SIRT5 (0.53) FOLH1SIRT5GNPATIL23R
SCHEMBL31157760 0.94 SIRT5 (0.53) FOLH1SIRT5GNPATIL23R
SCHEMBL31157647 0.94 SIRT5 (0.53) FOLH1SIRT5GNPATIL23R
SCHEMBL12066140 0.94 SIRT5 (0.53) FOLH1SIRT5GNPATIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161409-A1 COMPOSITIONS FOR TREATING HYPERHIDROSIS PROSPERA BIOTECH, S.L. (ES) 2025-05-22 US disclosed
EP-3852781-B1 COMPOSITIONS COMPRISING ACYLATED TETRAPEPTIDES FOR DERMATOLOGICAL AND COSMETIC APPLICATIONS MILLER NORMAN E (GB) 2025-03-19 EP disclosed
CN-113015538-B Compositions comprising acylated tetrapeptides for dermatological and cosmetic applications 诺曼·E·米勒 2025-01-14 CN disclosed
EP-3548510-B1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MAT INC (US) 2024-10-02 EP disclosed
EP-4362904-A1 COSMETIC, NON-THERAPEUTIC USES OF PEPTIDES Lubrizol Advanced Materials, Inc. (US) 2024-05-08 EP disclosed
CN-110997696-B Cosmetic composition for improving skin comprising fusion protein to which skin permeation promoting peptide is bound 株式会社LG生活健康 2024-03-05 CN disclosed
EP-4247835-A1 TETRAPEPTIDES, COMPOSITIONS COMPRISING THEM, AND THEIR COSMETIC USE SEDERMA (FR) 2023-09-27 EP disclosed
US-20230190616-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-06-22 US disclosed
EP-4188319-A1 COSMETIC OR DERMATOLOGICAL PEPTIDE-BASED TREATMENT OF THE SKIN AND ITS INTEGUMENTS SEDERMA (FR) 2023-06-07 EP disclosed
CN-111620928-B Large-scale synthesis method of hexapeptide 陕西慧康生物科技有限责任公司 2023-02-28 CN disclosed
EP-4120998-A1 COSMETIC COMPOSITION AND TREATMENT FOR TREATING SKIN SAGGING SEDERMA (FR) 2023-01-25 EP disclosed
WO-2023275811-A1 COSMETIC, NON-THERAPEUTIC USES OF PEPTIDES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-01-05 WO disclosed
EP-4076367-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION ACTING IN PARTICULAR ON THE EFFECTS OF BLUE LIGHT ON SKIN AND ITS APPENDAGES, AND ASSOCIATED USES SEDERMA (FR) 2022-10-26 EP disclosed
CN-111714395-B Polypeptide composition compounded by ginkgo biloba extract and application thereof 南京斯拜科生物科技股份有限公司 2022-10-04 CN disclosed
EP-4041184-A2 PEPTIDE BASED COSMETIC OR DERMATOLOGICAL TREATMENT OF THE SKIN AND ITS APPENDAGES SEDERMA (FR) 2022-08-17 EP disclosed
EP-4037656-A1 USE OF LEONTODIUM ALPINUM PLANT CELLS FOR AN ANTI-GLYCATION ANTI-AGEING SKIN TREATMENT SEDERMA (FR) 2022-08-10 EP disclosed
WO-2022106365-A1 TETRAPEPTIDES, COMPOSITIONS COMPRISING THEM, AND THEIR COSMETIC USE SEDERMA (FR) 2022-05-27 WO disclosed
CN-114555045-A Peptide-based cosmetic or dermatological treatment of skin and its appendages 赛德玛公司 2022-05-27 CN disclosed
CN-114057838-B Solid-phase synthesis method of acetyl hexapeptide-8 浙江湃肽生物有限公司南京分公司 2022-04-12 CN disclosed
CN-114057838-A Solid-phase synthesis method of acetyl hexapeptide-8 浙江湃肽生物有限公司南京分公司 2022-02-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190616-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES GLA, ALG3, ANXA6 FOLH1 3861/4885SIRT5 3611/4885GNPAT 3557/4885
US-20250161409-A1 COMPOSITIONS FOR TREATING HYPERHIDROSIS TRPV1, NHERF1, SLC18A1 FOLH1 3790/4885SIRT5 4118/4885GNPAT 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.