Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919374 | 0.67 | NPC1 (0.38) | SMN1; SMN2PTGS1PTGS2OPRK1HTT | |
| SCHEMBL5076283 | 0.65 | HTR2A (0.39) | SMN1; SMN2NPSR1PDE7BHTR2AHTR2C | |
| SCHEMBL350067 | 0.60 | PTGS2 (0.71) | PTGS1PTGS2KMT2AHTR2A | |
| SCHEMBL599316 | 0.60 | PTGS2 (0.71) | PTGS1PTGS2KMT2AHTR2A | |
| SCHEMBL2370631 | 0.60 | PTGS2 (0.71) | PTGS1PTGS2KMT2AHTR2A | |
| SCHEMBL28662721 | 0.59 | PTGS2 (0.69) | PTGS1PTGS2KMT2AHTR2A | |
| SCHEMBL1678493 | 0.57 | PTGS2 (0.67) | PTGS1PTGS2 | |
| SCHEMBL10825032 | 0.56 | PTGS2 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL14117530 | 0.56 | ALDH1A1 (0.46) | SMN1; SMN2NPSR1OPRK1KMT2AHTR2A | |
| Ibuprofen SCHEMBL6273340 | 0.56 | PTGS1 (0.89) | PTGS1PTGS2HTR2AMT-CO1MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979355-B1 | SPIRO IMIDAZOLE DERIVATIVES AS PPAR MODULATORS | IRM LLC (BM) | 2010-08-18 | — | — | EP | claimed |