Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | TPO | P07202 | 1/20 | 0.32 |
| ▸ | GCKR | Q14397 | 3/20 | 0.31 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429693 | 0.82 | ADORA2B (0.44) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL29429688 | 0.70 | ADORA2B (0.43) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL30753411 | 0.65 | ADORA2A (0.62) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL9317914 | 0.65 | ADORA2A (0.62) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL4459832 | 0.64 | MPO (0.46) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL6663821 | 0.63 | PNP (0.61) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL10980302 | 0.63 | ADORA2A (0.72) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL864455 | 0.63 | ADORA2A (0.58) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL237146 | 0.63 | ADORA2A (0.64) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL5513199 | 0.63 | ADORA2A (0.58) | PDE4AADORA2APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |
| EP-3205652-B1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG RAYNOVENT BIOTECH CO LTD (CN) | 2022-03-09 | — | — | EP | disclosed |