SCHEMBL2943192

SCHEMBL2943192

Fc1cc(-c2[c]cc(F)c(F)c2F)ccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.35
EGLN2 Q96KS0 1/20 0.34
FFAR1 O14842 1/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
ERCC5 P28715 1/20 0.31
FEN1 P39748 1/20 0.31
ABL1 P00519 1/20 0.31
AHR P35869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5798197 0.83 NOTUM (0.35) KMO
SCHEMBL29993075 0.73 AHR (0.55) KMOEGLN2FFAR1PTGS1PTGS2
SCHEMBL3934141 0.69 PTGS2 (0.39) KMOPTGS1PTGS2
SCHEMBL1275684 0.68 PTGS2 (0.35) KMOEGLN2PTGS1PTGS2ERCC5
SCHEMBL1275685 0.68 AHR (0.38) KMOEGLN2FFAR1PTGS1PTGS2
SCHEMBL4006606 0.67
SCHEMBL31067094 0.66 AHR (0.46) KMOEGLN2FFAR1PTGS1PTGS2
SCHEMBL533100 0.66 AHR (0.41) KMOEGLN2FFAR1PTGS1PTGS2
SCHEMBL30936103 0.65 ESR2 (0.52) KMOEGLN2FFAR1ERCC5FEN1
SCHEMBL1042848 0.65 ESR2 (0.52) KMOEGLN2FFAR1ERCC5FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183897-A9 MUCIN GLYCANS AS ANTIFUNGAL AGENTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-07-11 WO disclosed
US-20230321186-A1 Mucin Glycans as Antifungal Agents UNIVERSITÄT BASEL (CH) 2023-10-12 US disclosed
WO-2023183897-A1 MUCIN GLYCANS AS ANTIFUNGAL AGENTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-09-28 WO disclosed
EP-2508888-A1 Method for diagnosing a hepatic disease by sugar chain analysis National University Corporation Hokkaido University (JP) 2012-10-10 EP disclosed
US-20100301203-A1 METHOD OF DIAGNOSTIC HEPARIC DISEASE BY SUGAR CHAIN ANALYSIS NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2010-12-02 US disclosed
EP-2224235-A1 METHOD OF DIAGNOSTIC HEPATIC DISEASE BY SUGAR CHAIN ANALYSIS National University Corporation Hokkaido University (JP) 2010-09-01 EP disclosed
EP-2216025-A2 Use of acylaminoalkenylene-amide derivatives in irritable bowel syndrome and functional dyspepsia Novartis AG (CH) 2010-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321186-A1 Mucin Glycans as Antifungal Agents MUC1, FUT5, FUT8 KMO 1489/4885EGLN2 4716/4885FFAR1 3652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.