Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863579 | 1.00 | P2RX1 (0.40) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL16863609 | 0.95 | P2RX1 (0.38) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL16870251 | 0.89 | MEN1 (0.40) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29695888 | 0.89 | LMNA (0.41) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL16863578 | 0.89 | LMNA (0.41) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1766957 | 0.89 | P2RX1 (0.41) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29549629 | 0.89 | P2RX1 (0.41) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29695977 | 0.89 | P2RX1 (0.41) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1767290 | 0.88 | P2RX1 (0.47) | P2RX1MAPTLMNAMEN1KMT2A | |
| SCHEMBL28567825 | 0.86 | P2RX1 (0.38) | P2RX1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220081389-A1 | AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC NANTONG CHEMICAL CO., LTD (CN) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081389-A1 | AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, VIP, NOTUM | P2RX1 2917/4885MAPT 4214/4885LMNA 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.