SCHEMBL1766957

SCHEMBL1766957

O=C(Nc1c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1OC(F)(F)F)c1cccc([N+](=O)[O-])c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 2/20 0.41
MAPT P10636 4/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
TDP1 Q9NUW8 1/20 0.38
RAB9A P51151 1/20 0.38
KCNMA1 Q12791 2/20 0.37
BRAF P15056 1/20 0.37
CYP2C9 P11712 2/20 0.36
KCNK3 O14649 2/20 0.36
KCNK9 Q9NPC2 2/20 0.36
DHODH Q02127 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
CCR6 P51684 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
HTT P42858 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549629 1.00 P2RX1 (0.41) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL29695977 1.00 P2RX1 (0.41) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL1767132 0.91 P2RX1 (0.40) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL1767290 0.90 P2RX1 (0.47) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL13508274 0.89 KCNMA1 (0.44) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL16863579 0.89 P2RX1 (0.40) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL29431920 0.89 P2RX1 (0.40) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL20839536 0.89 P2RX1 (0.41) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL31175825 0.86 KMT2A (0.47) P2RX1MAPTLMNAMEN1KMT2A
SCHEMBL29257321 0.86 P2RX1 (0.47) P2RX1MAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3684181-B1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2025-10-22 EP disclosed
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-08-05 US disclosed
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-07-20 US disclosed
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MITSUI CHEMICALS AGRO, INC. (JP) 2023-07-11 US disclosed
US-11407710-B2 Method for preparing an N-cyclopropylmethyl aniline compound Jiangxi Univate New Material Co., LTD. 2022-08-09 US disclosed
US-20220202011-A1 PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF JIANGSU YANGNONG CHEMICAL CO., LTD (CN) 2022-06-30 US disclosed
US-20220177414-A1 METHOD FOR PREPARING AN N-CYCLOPROPYLMETHYL ANILINE COMPOUND Jiangxi Univate New Material Co., LTD. (CN) 2022-06-09 US disclosed
CN-114591232-A Long-acting control agent for ectoparasites of animals 三井化学AGRO株式会社 2022-06-07 CN disclosed
CN-114591192-A Preparation method of N-cyclopropylmethylaniline compound 江西仰立新材料有限公司 2022-06-07 CN disclosed
CN-111132549-B Long-acting control agent for ectoparasites of animals 三井化学AGRO株式会社 2022-04-12 CN disclosed
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS ARGO, INC. (JP) 2013-09-05 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
CN-102119143-A Amide derivative, pest control agent containing the same, and method of using the pest control agent MITSUI CHEMICALS AGRO INC 2011-07-06 CN disclosed
CN-102112437-A Amide derivative, pest control agent containing same, and pest control method MITSUI CHEMICALS AGRO INC 2011-06-29 CN disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202011-A1 PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF ALDH7A1, CAT, PIR P2RX1 1040/4885MAPT 4115/4885LMNA 3541/4885
US-11696913-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT P2RX1 873/4885MAPT 3034/4885LMNA 3538/4885
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 P2RX1 4192/4885MAPT 4155/4885LMNA 1247/4885
US-11407710-B2 Method for preparing an N-cyclopropylmethyl aniline compound PPOX, HAAO, DAO P2RX1 1310/4885MAPT 3772/4885LMNA 626/4885
US-20230226037-A1 PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL MTX1, ENPP1, CAT P2RX1 873/4885MAPT 3034/4885LMNA 3538/4885
US-20220177414-A1 METHOD FOR PREPARING AN N-CYCLOPROPYLMETHYL ANILINE COMPOUND PPOX, HAAO, DAO P2RX1 1310/4885MAPT 3772/4885LMNA 626/4885
US-12377085-B2 Prolonged ectoparasite-controlling agent for animal MTX1, ENPP1, CAT P2RX1 873/4885MAPT 3034/4885LMNA 3538/4885
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 P2RX1 3026/4885MAPT 4647/4885LMNA 2595/4885
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-0, H1-4 P2RX1 3567/4885MAPT 4647/4885LMNA 2403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.