SCHEMBL1767290

SCHEMBL1767290

O=C(Nc1c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1Br)c1cccc([N+](=O)[O-])c1F

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 2/20 0.47
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
RAB9A P51151 1/20 0.43
KCNMA1 Q12791 3/20 0.42
CYP2C9 P11712 2/20 0.41
DHODH Q02127 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
PKM P14618 1/20 0.40
LMNA P02545 2/20 0.39
MAPT P10636 1/20 0.39
MDM2 Q00987 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1767400 0.95 P2RX1 (0.45) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL31175825 0.94 KMT2A (0.47) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL29257321 0.94 P2RX1 (0.47) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL1766786 0.93 P2RX1 (0.46) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL22497571 0.93 P2RX1 (0.43) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL16155805 0.93 P2RX1 (0.43) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL29615050 0.93 P2RX1 (0.46) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL1766978 0.92 P2RX1 (0.43) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL1766957 0.90 P2RX1 (0.41) P2RX1KMT2AMEN1RAB9AKCNMA1
SCHEMBL29695977 0.90 P2RX1 (0.41) P2RX1KMT2AMEN1RAB9AKCNMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872904-B N-hydroxy-N-phenyl aromatic amide derivative and application thereof 沈阳中化农药化工研发有限公司 2024-06-25 CN disclosed
CN-116621727-A Aryl or heteroaryl substituted meta-diamide compound or salt acceptable as pesticide, composition and application thereof 海利尔药业集团股份有限公司 2023-08-22 CN disclosed
CN-115872904-A N-hydroxy-N-phenyl aromatic amide derivative and application thereof 沈阳中化农药化工研发有限公司 2023-03-31 CN disclosed
CN-109206397-B Piperamic acid derivative and preparation and application thereof 沈阳中化农药化工研发有限公司 2022-06-07 CN disclosed
EP-3205642-B1 ANILINE INTERMEDIATE FOR THE PREPARATION OF AN AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE. MITSUI CHEMICALS AGRO INC (JP) 2022-03-23 EP disclosed
EP-3647305-B1 PIPERIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) 2022-02-23 EP disclosed
EP-3081552-B1 PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT MITSUI CHEMICALS AGRO INC (JP) 2021-03-03 EP disclosed
EP-2529620-B1 COMPOSITION FOR CONTROL OF ANIMAL PARASITES, AND METHOD FOR CONTROL OF ANIMAL PARASITES MITSUI CHEMICALS AGRO INC (JP) 2020-07-15 EP disclosed
US-20200181107-A1 PIPERONYLIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2020-06-11 US disclosed
EP-3647305-A1 PIPERIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2020-05-06 EP disclosed
US-9084420-B2 Amide derivative, pest control agent containing the amide derivative, and pest controlling method MITSUI CHEMICALS AGRO, INC. (JP) 2015-07-21 US disclosed
US-20140107368-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD MITSUI CHEMICALS AGRO, INC. (JP) 2014-04-17 US disclosed
US-8633228-B2 Amide derivative, pest control agent containing the amide derivative, and pest controlling method MITSUI CHEMICALS AGRO, INC. (JP) 2014-01-21 US disclosed
US-20130310459-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2013-11-21 US disclosed
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS ARGO, INC. (JP) 2013-09-05 US disclosed
EP-2529620-A1 COMPOSITION FOR CONTROL OF ANIMAL PARASITES, AND METHOD FOR CONTROL OF ANIMAL PARASITES Mitsui Chemicals Agro, Inc. (JP) 2012-12-05 EP disclosed
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS AGRO, INC. (JP) 2011-08-18 US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 US disclosed
EP-2325165-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2011-05-25 EP disclosed
EP-2319830-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2011-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 P2RX1 4192/4885KMT2A 134/4885MEN1 3215/4885
US-20140107368-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 P2RX1 4192/4885KMT2A 134/4885MEN1 3215/4885
US-20200181107-A1 PIPERONYLIC ACID DERIVATIVE AND PREPARATION AND APPLICATION THEREOF CYP51A1, DDT, PIR P2RX1 1030/4885KMT2A 2382/4885MEN1 2081/4885
US-20130310459-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-0, H1-4 P2RX1 3567/4885KMT2A 262/4885MEN1 3310/4885
US-20110201687-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 P2RX1 3026/4885KMT2A 333/4885MEN1 3163/4885
US-20130231392-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-0, H1-4 P2RX1 3567/4885KMT2A 262/4885MEN1 3310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.