Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432912 | 0.88 | RAB9A (1.00) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL29432916 | 0.88 | RAB9A (1.00) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL8566715 | 0.86 | KDM4E (1.00) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL4938762 | 0.80 | RAB9A (0.68) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL29432961 | 0.80 | KDM4E (0.61) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL29432985 | 0.80 | KDM4E (0.61) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL29432950 | 0.79 | KDM4E (0.60) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL29433003 | 0.79 | KDM4E (0.60) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL29432980 | 0.79 | KDM4E (0.60) | RAB9APOLBLMNATSHRHSD17B10 | |
| SCHEMBL20509078 | 0.78 | HDAC1 (0.76) | RAB9APOLBLMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058327-A1 | SUBSTITUTED UREAS AND DERIVATIVES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-03-24 | — | — | WO | disclosed |