Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | FLT1 | P17948 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29433014 | 1.00 | KDM4E (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29432985 | 0.80 | KDM4E (0.61) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29432961 | 0.80 | KDM4E (0.61) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29432939 | 0.79 | RAB9A (0.78) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29432950 | 0.77 | KDM4E (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL29432980 | 0.77 | KDM4E (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8566715 | 0.76 | KDM4E (1.00) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL25373077 | 0.74 | KDM4E (0.60) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL15452593 | 0.74 | OPRM1 (0.48) | RAB9ANPC1HSD17B10LMNAOPRM1 | |
| SCHEMBL29432916 | 0.73 | RAB9A (1.00) | KDM4ERAB9ANPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058327-A1 | SUBSTITUTED UREAS AND DERIVATIVES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-03-24 | — | — | WO | disclosed |