SCHEMBL29434201

SCHEMBL29434201

COc1cc(F)c([C@@H]2CN(C)C(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 17/20 0.70
FPR1 P21462 17/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18106415 1.00 FPR2 (0.70) FPR2FPR1
SCHEMBL18106417 1.00 FPR2 (0.70) FPR2FPR1
SCHEMBL20041884 1.00 FPR2 (0.70) FPR2FPR1
SCHEMBL18106666 0.93 FPR1 (0.70) FPR2FPR1
SCHEMBL29434447 0.93 FPR1 (0.70) FPR2FPR1
SCHEMBL18106668 0.93 FPR1 (0.70) FPR2FPR1
SCHEMBL18106534 0.89 FPR1 (0.72) FPR2FPR1
SCHEMBL29434049 0.89 FPR1 (0.72) FPR2FPR1
SCHEMBL18106531 0.89 FPR1 (0.72) FPR2FPR1
SCHEMBL18106469 0.88 FPR2 (0.68) FPR2FPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11261155-B2 Urea derivative or pharmacologically acceptable salt thereof KYORIN PHARMACEUTICAL CO., LTD. (JP) 2022-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11261155-B2 Urea derivative or pharmacologically acceptable salt thereof FPR1, FPR2, FPR3 FPR2 2/4885FPR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.