Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283019 | 1.00 | MEN1 (0.38) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL3397719 | 0.83 | IDO1 (0.34) | KMT2AALDH1A1L3MBTL1IDO1PNMT | |
| SCHEMBL2297312 | 0.82 | XDH (0.47) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL1780435 | 0.80 | IDO1 (0.54) | KMT2ALMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28879804 | 0.80 | PTPRC (0.36) | — | |
| SCHEMBL31076402 | 0.77 | MEN1 (0.36) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL15516408 | 0.76 | L3MBTL1 (0.33) | L3MBTL1IDO1CYP3A4CA2PNMT | |
| SCHEMBL17336260 | 0.76 | — | — | |
| SCHEMBL507688 | 0.76 | CYP4F2 (0.40) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL1535743 | 0.76 | IDO1 (0.38) | MEN1KMT2ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110225911-B | Oxadiazolone transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-04-05 | — | — | CN | disclosed |