Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283019 | 0.82 | MEN1 (0.38) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL29434764 | 0.82 | MEN1 (0.38) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL30271269 | 0.81 | IDO1 (0.52) | XDHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11043517 | 0.81 | IDO1 (0.52) | XDHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7081107 | 0.77 | XDH (0.38) | XDHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3754842 | 0.77 | KMT2A (0.40) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL2295101 | 0.76 | XDH (0.47) | XDHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1738367 | 0.76 | ALDH1A1 (0.47) | XDHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4576820 | 0.76 | XDH (0.68) | XDHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9514553 | 0.76 | XDH (0.47) | XDHALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103063-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-08-25 | — | — | WO | disclosed |