SCHEMBL29436295

SCHEMBL29436295

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 11/20 0.56
▸ TLR2 O60603 4/20 0.56
▸ ERAP2 Q6P179 1/20 0.52
▸ NPBWR1 P48145 1/20 0.52
▸ IL23R Q5VWK5 2/20 0.51
▸ GLP1R P43220 1/20 0.51
▸ GCGR P47871 1/20 0.51
▸ GIPR P48546 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728785 0.93 IL23R (0.57) KISS1RTLR2IL23RGLP1RGCGR
SCHEMBL30108349 0.91 KISS1R (0.55) KISS1RTLR2ERAP2IL23R
SCHEMBL29393516 0.91 ERAP2 (0.56) KISS1RERAP2
SCHEMBL29607306 0.91 TLR2 (0.59) KISS1RTLR2IL23RGLP1RGCGR
SCHEMBL29970258 0.90 GLP1R (0.63) TLR2IL23RGLP1RGCGRGIPR
SCHEMBL29608081 0.89 GLP1R (0.62) KISS1RTLR2IL23RGLP1RGCGR
SCHEMBL31047373 0.88 KISS1R (0.57) KISS1RIL23R
SCHEMBL30262138 0.88 TLR2 (0.61) TLR2GLP1RGCGRGIPR
SCHEMBL32667969 0.87 ERAP2 (0.60) KISS1RERAP2
SCHEMBL31182787 0.85 GLP1R (0.65) KISS1RTLR2IL23RGLP1RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236142-B2 Acylated oxyntomodulin peptide analog DONG-A ST CO., LTD. (KR) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236142-B2 Acylated oxyntomodulin peptide analog GLP1R, GIPR, GPR119 KISS1R 179/4885TLR2 483/4885ERAP2 454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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