SCHEMBL29607306

SCHEMBL29607306

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 4/20 0.59
▸ GLP1R P43220 1/20 0.56
▸ GCGR P47871 1/20 0.56
▸ GIPR P48546 1/20 0.56
▸ KISS1R Q969F8 6/20 0.56
▸ IL23R Q5VWK5 5/20 0.56
▸ MAGI3 Q5TCQ9 1/20 0.52
▸ NPY2R P49146 2/20 0.52
▸ GHSR Q92847 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390396 0.92 MAGI3 (0.55) TLR2KISS1RIL23RMAGI3
SCHEMBL29608081 0.91 GLP1R (0.62) TLR2GLP1RGCGRGIPRKISS1R
SCHEMBL29436295 0.91 KISS1R (0.56) TLR2GLP1RGCGRGIPRKISS1R
SCHEMBL31597621 0.89 ERAP2 (0.56) TLR2KISS1RIL23RMAGI3GHSR
SCHEMBL30601285 0.89 GLP1R (0.64) TLR2GLP1RGCGRGIPRKISS1R
SCHEMBL30262080 0.89 TLR2 (0.59) TLR2GLP1RGCGRGIPRMAGI3
SCHEMBL30512677 0.87 MAGI3 (0.62) TLR2GLP1RGCGRGIPRIL23R
SCHEMBL30608430 0.87 ERAP2 (0.58) TLR2KISS1RIL23RMAGI3GHSR
SCHEMBL29609550 0.87 ERAP2 (0.60) TLR2KISS1RIL23RMAGI3NPY2R
SCHEMBL31694490 0.87 IL23R (0.57) TLR2GLP1RGCGRGIPRKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713344-B2 Acylated oxyntomodulin peptide analog DONG-A ST CO., LTD. (KR) 2023-08-01 — — US disclosed
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG DONG-A ST CO., LTD. (KR) 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11713344-B2 Acylated oxyntomodulin peptide analog GLP1R, GIPR, GPR119 TLR2 1131/4885GLP1R 1/4885GCGR 5/4885
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG GLP1R, GIPR, GPR119 TLR2 1131/4885GLP1R 1/4885GCGR 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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