SCHEMBL29436306

SCHEMBL29436306

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)O)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.54
▸ OPRD1 P41143 4/20 0.54
▸ OPRK1 P41145 1/20 0.52
▸ BACE1 P56817 3/20 0.49
▸ OPRL1 P41146 1/20 0.49
▸ BACE2 Q9Y5Z0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674783 0.95 OPRM1 (0.53) OPRM1OPRD1OPRK1BACE1OPRL1
SCHEMBL29436286 0.94 OPRM1 (0.55) OPRM1OPRD1OPRK1OPRL1
SCHEMBL31347335 0.93 OPRL1 (0.56) OPRM1OPRD1OPRK1OPRL1
SCHEMBL29375740 0.91 BACE1 (0.56) OPRM1OPRD1BACE1BACE2
SCHEMBL29375389 0.91 BACE1 (0.56) OPRM1OPRD1BACE1BACE2
SCHEMBL29378801 0.91 BACE1 (0.54) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL30721650 0.90 OPRM1 (0.55) OPRM1OPRD1OPRK1OPRL1
SCHEMBL29375819 0.90 OPRM1 (0.54) OPRM1OPRD1OPRK1BACE1OPRL1
SCHEMBL31347347 0.88 GLP1R (0.51) OPRM1OPRD1OPRK1
SCHEMBL29695617 0.86 OPRM1 (0.63) OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11713344-B2 Acylated oxyntomodulin peptide analog DONG-A ST CO., LTD. (KR) 2023-08-01 — — US claimed
EP-4079757-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG Dong-A St Co., Ltd. (KR) 2022-10-26 — — EP claimed
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG DONG-A ST CO., LTD. (KR) 2022-04-21 — — US claimed
US-11713344-B2 Acylated oxyntomodulin peptide analog DONG-A ST CO., LTD. (KR) 2023-08-01 — — US disclosed
EP-4079757-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG Dong-A St Co., Ltd. (KR) 2022-10-26 — — EP disclosed
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG DONG-A ST CO., LTD. (KR) 2022-04-21 — — US disclosed
US-11236142-B2 Acylated oxyntomodulin peptide analog DONG-A ST CO., LTD. (KR) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11713344-B2 Acylated oxyntomodulin peptide analog GLP1R, GIPR, GPR119 OPRM1 76/4885OPRD1 88/4885OPRK1 156/4885
US-20220119473-A1 ACYLATED OXYNTOMODULIN PEPTIDE ANALOG GLP1R, GIPR, GPR119 OPRM1 76/4885OPRD1 88/4885OPRK1 156/4885
US-11236142-B2 Acylated oxyntomodulin peptide analog GLP1R, GIPR, GPR119 OPRM1 79/4885OPRD1 112/4885OPRK1 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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