SCHEMBL29378801

SCHEMBL29378801

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 5/20 0.54
▸ OPRM1 P35372 3/20 0.49
▸ OPRD1 P41143 3/20 0.49
▸ BACE2 Q9Y5Z0 1/20 0.49
▸ OPRK1 P41145 1/20 0.48
▸ CTSD P07339 1/20 0.48
▸ ENPEP Q07075 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29804647 0.95 BACE1 (0.51) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL29674783 0.95 OPRM1 (0.53) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL30299009 0.95 OPRM1 (0.55) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL29804763 0.94 OPRM1 (0.57) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL30477365 0.93 OPRD1 (0.58) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL30376274 0.92 OPRD1 (0.54) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL29375389 0.92 BACE1 (0.56) BACE1OPRM1OPRD1BACE2CTSD
SCHEMBL29375740 0.92 BACE1 (0.56) BACE1OPRM1OPRD1BACE2CTSD
SCHEMBL29436306 0.91 OPRM1 (0.54) BACE1OPRM1OPRD1BACE2OPRK1
SCHEMBL29375819 0.91 OPRM1 (0.54) BACE1OPRM1OPRD1BACE2OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2024-06-27 — — US claimed
US-11814417-B2 GIP agonist compounds and methods ZEALAND PHARMA A/S (DK) 2023-11-14 — — US claimed
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2022-02-10 — — US claimed
EP-4593864-A1 METHODS FOR TREATING OBESITY Zealand Pharma A/S (DK) 2025-08-06 — — EP disclosed
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2024-06-27 — — US disclosed
WO-2024068848-A1 METHODS FOR TREATING OBESITY ZEALAND PHARMA A/S (DK) 2024-04-04 — — WO disclosed
US-11814417-B2 GIP agonist compounds and methods ZEALAND PHARMA A/S (DK) 2023-11-14 — — US disclosed
EP-4144362-A1 COMPOSITIONS COMPRISING SHORT-ACTING HORMONES FOR TREATING OR PREVENTING OBESITY AND PUMPS COMPRISING SAID COMPOSITION Adocia (FR) 2023-03-08 — — EP disclosed
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209054-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 BACE1 3779/4885OPRM1 1117/4885OPRD1 1008/4885
US-11814417-B2 GIP agonist compounds and methods GIPR, GLP1R, GPR119 BACE1 3779/4885OPRM1 1117/4885OPRD1 1008/4885
US-20220041676-A1 GIP AGONIST COMPOUNDS AND METHODS GIPR, GLP1R, GPR119 BACE1 3779/4885OPRM1 1117/4885OPRD1 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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