Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 4/20 | 0.47 |
| ▸ | BAZ2A | Q9UIF9 | 4/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296856 | 0.80 | BAZ2B (0.42) | BAZ2BBAZ2ABRD9BTK | |
| SCHEMBL30231159 | 0.79 | SLC9A1 (0.42) | — | |
| SCHEMBL6303170 | 0.78 | MKNK1 (0.54) | BAZ2BBAZ2ABRD9L3MBTL1 | |
| SCHEMBL5171111 | 0.78 | BAZ2B (0.50) | BAZ2BBAZ2ABRD9KMT2APDK2 | |
| SCHEMBL16990464 | 0.76 | SLC9A1 (0.44) | — | |
| SCHEMBL16618470 | 0.76 | PTGS2 (0.47) | MEN1KMT2AL3MBTL1BCAT2 | |
| SCHEMBL3830207 | 0.75 | BAZ2B (0.40) | BAZ2BBAZ2ABRD9BTKALOX5AP | |
| SCHEMBL4732438 | 0.74 | BCAT2 (0.47) | BRD4BCAT2JAK2 | |
| SCHEMBL5608689 | 0.74 | PARP1 (0.47) | MEN1KMT2AL3MBTL1BTKPDK2 | |
| SCHEMBL364343 | 0.73 | BCAT2 (0.56) | BCAT2JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940786-B1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LTD (GB) | 2010-08-18 | — | — | EP | disclosed |