Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.71 |
| ▸ | RORC | P51449 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | APAF1 | O14727 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450615 | 0.88 | BRD4 (0.73) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28458415 | 0.87 | BRD4 (0.65) | BRD4RORCALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14527675 | 0.86 | BRD4 (0.71) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29437286 | 0.86 | BRD4 (0.75) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL16862798 | 0.86 | BRD4 (0.75) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29437320 | 0.84 | BRD4 (0.80) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL17992491 | 0.84 | BRD4 (0.80) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL17992497 | 0.83 | BRD4 (1.00) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL11213051 | 0.82 | BRD4 (0.65) | BRD4ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29437293 | 0.81 | BRD4 (1.00) | BRD4RORCALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662226-B | 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound | 中国科学院广州生物医药与健康研究院 | 2022-03-18 | — | — | CN | disclosed |