SCHEMBL29437909

SCHEMBL29437909

CCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2CC)c(F)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 18/20 0.60
AGTR1 P30556 2/20 0.51
CYP3A4 P08684 2/20 0.49
MEN1 O00255 1/20 0.49
GMNN O75496 1/20 0.49
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
APEX1 P27695 1/20 0.49
CYP2C19 P33261 1/20 0.49
THPO P40225 1/20 0.49
MTOR P42345 1/20 0.49
RECQL P46063 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23121256 1.00 AGTR2 (0.60) AGTR2AGTR1CYP3A4MEN1GMNN
SCHEMBL29047290 0.94 AGTR2 (0.58) AGTR2AGTR1CYP3A4
SCHEMBL29047260 0.94 AGTR2 (0.62) AGTR2AGTR1CYP3A4MEN1GMNN
SCHEMBL25248583 0.93 AGTR2 (0.55) AGTR2CYP3A4
SCHEMBL29047244 0.92 AGTR2 (0.69) AGTR2AGTR1CYP3A4CYP2C9
SCHEMBL29437899 0.92 AGTR2 (0.69) AGTR2AGTR1CYP3A4CYP2C9
SCHEMBL29437916 0.92 AGTR2 (0.61) AGTR2AGTR1CYP2C9
SCHEMBL29437903 0.92 AGTR2 (0.61) AGTR2AGTR1CYP2C9
SCHEMBL29047252 0.92 AGTR2 (0.57) AGTR2AGTR1
SCHEMBL29047242 0.91 AGTR2 (0.60) AGTR2AGTR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-11-02 US claimed
CN-116568682-A Novel compounds for the treatment of angiotensin II related diseases 维科尔药物公司 2023-08-08 CN claimed
EP-4208460-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-07-12 EP claimed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 WO claimed
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-11-02 US disclosed
CN-116568682-A Novel compounds for the treatment of angiotensin II related diseases 维科尔药物公司 2023-08-08 CN disclosed
EP-4208460-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-07-12 EP disclosed
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP disclosed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II AGTR1, AGTR2, REN AGTR2 2/4885AGTR1 1/4885CYP3A4 3043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.