SCHEMBL29437910

SCHEMBL29437910

CCc1nccn1Cc1ccc(-c2cc(CC(C)C)sc2S(N)(=O)=O)cc1F

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.46
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23121345 1.00 AGTR2 (0.46) AGTR2CYP3A4
SCHEMBL25248505 0.89 AGTR2 (0.51) AGTR2CYP3A4
SCHEMBL29437911 0.89 AGTR2 (0.51) AGTR2CYP3A4
SCHEMBL29047266 0.89 AGTR2 (0.47) AGTR2CYP3A4
SCHEMBL29437919 0.88 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL25292058 0.88 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL25248583 0.88 AGTR2 (0.55) AGTR2CYP3A4
SCHEMBL25254599 0.88 AGTR2 (0.48) AGTR2CYP3A4
SCHEMBL30195104 0.88 AGTR2 (0.54) AGTR2
SCHEMBL30645006 0.87 AGTR2 (0.44) AGTR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313976-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS Vicore Pharma AB (SE) 2024-02-07 EP disclosed
CN-116568682-A Novel compounds for the treatment of angiotensin II related diseases 维科尔药物公司 2023-08-08 CN disclosed
EP-4208460-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-07-12 EP disclosed
WO-2022200786-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2022-09-29 WO disclosed
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP disclosed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 WO disclosed