SCHEMBL29437911

SCHEMBL29437911

Cc1nccn1Cc1ccc(-c2cc(CC(C)C)sc2S(N)(=O)=O)cc1F

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.51
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25248505 1.00 AGTR2 (0.51) AGTR2CYP3A4
SCHEMBL27083129 0.92 AGTR2 (0.50) AGTR2CYP3A4
SCHEMBL29047366 0.92 AGTR2 (0.52) AGTR2CYP3A4
SCHEMBL30476540 0.92 AGTR2 (0.52) AGTR2CYP3A4
SCHEMBL26124846 0.91 AGTR2 (0.52) AGTR2CYP3A4
SCHEMBL25292058 0.90 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL29437919 0.90 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL23121345 0.89 AGTR2 (0.46) AGTR2CYP3A4
SCHEMBL29437910 0.89 AGTR2 (0.46) AGTR2CYP3A4
SCHEMBL30970211 0.89 AGTR2 (0.53) AGTR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441718-B2 Selective angiotensin II compounds VICORE PHARMA AB (SE) 2025-10-14 US claimed
US-20250101010-A1 SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2025-03-27 US claimed
EP-4313976-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS Vicore Pharma AB (SE) 2024-02-07 EP disclosed
CN-116568682-A Novel compounds for the treatment of angiotensin II related diseases 维科尔药物公司 2023-08-08 CN disclosed
EP-4208460-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-07-12 EP disclosed
WO-2022200786-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2022-09-29 WO disclosed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101010-A1 SELECTIVE ANGIOTENSIN II COMPOUNDS AGTR1, AGTR2, REN AGTR2 2/4885CYP3A4 1319/4885
US-12441718-B2 Selective angiotensin II compounds AGTR1, AGTR2, REN AGTR2 2/4885CYP3A4 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.