SCHEMBL25254599

SCHEMBL25254599

CCc1nccn1Cc1ccc(-c2cc(CC(C)C)sc2S(=O)(=O)NC(C)(C)C)cc1F

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.48
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23121227 0.94 AGTR2 (0.45) AGTR2CYP3A4
SCHEMBL25293677 0.90 AGTR2 (0.52) AGTR2CYP3A4
SCHEMBL25248847 0.89 AGTR2 (0.54) AGTR2CYP3A4
SCHEMBL25246111 0.89 AGTR2 (0.47) AGTR2CYP3A4
SCHEMBL30195104 0.89 AGTR2 (0.54) AGTR2
SCHEMBL25248583 0.89 AGTR2 (0.55) AGTR2CYP3A4
SCHEMBL23121345 0.88 AGTR2 (0.46) AGTR2CYP3A4
SCHEMBL29437910 0.88 AGTR2 (0.46) AGTR2CYP3A4
SCHEMBL26129333 0.88 AGTR2 (0.46) AGTR2CYP3A4
SCHEMBL27083129 0.87 AGTR2 (0.50) AGTR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-11-02 US disclosed
EP-4208460-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-07-12 EP disclosed
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP disclosed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II AGTR1, AGTR2, REN AGTR2 2/4885CYP3A4 3043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.