SCHEMBL29437917

SCHEMBL29437917

Cc1nccn1Cc1ccc(-c2cc(CC(C)C)sc2S(=O)(=O)NC(=O)OCC(C)(C)O)cc1F

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.63
CYP3A4 P08684 1/20 0.51
AGTR1 P30556 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29047365 1.00 AGTR2 (0.63) AGTR2CYP3A4AGTR1
SCHEMBL29047248 0.92 AGTR2 (0.61) AGTR2CYP3A4
SCHEMBL29047244 0.92 AGTR2 (0.69) AGTR2CYP3A4AGTR1
SCHEMBL29437899 0.92 AGTR2 (0.69) AGTR2CYP3A4AGTR1
SCHEMBL29047268 0.90 AGTR2 (0.64) AGTR2CYP3A4
SCHEMBL29437897 0.90 AGTR2 (0.64) AGTR2CYP3A4
SCHEMBL25286063 0.90 AGTR2 (0.65) AGTR2CYP3A4AGTR1
SCHEMBL29047258 0.90 AGTR2 (0.70) AGTR2AGTR1
SCHEMBL29437901 0.90 AGTR2 (0.70) AGTR2AGTR1
Trifluoroacetic Acid SCHEMBL25297677 0.89 AGTR2 (0.64) AGTR2CYP3A4AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2023-11-02 US disclosed
EP-4208460-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II Vicore Pharma AB (SE) 2023-07-12 EP disclosed
WO-2022049372-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II VICORE PHARMA AB (SE) 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348444-A1 NOVEL COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOTENSIN II AGTR1, AGTR2, REN AGTR2 2/4885CYP3A4 3043/4885AGTR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.