Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437959 | 1.00 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1PLA2G4ATLR7HDAC1 | |
| SCHEMBL14983987 | 0.89 | KDM1A (0.34) | ALDH1A1TLR7HDAC1HDAC8HDAC6 | |
| SCHEMBL19389074 | 0.85 | ABCB1 (0.39) | ALDH1A1TLR7HDAC1HDAC8HDAC6 | |
| SCHEMBL12879880 | 0.85 | ABCB1 (0.39) | ALDH1A1TLR7HDAC1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL28631038 | 0.84 | ABCB1 (0.38) | ALDH1A1TLR7HDAC1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL28631036 | 0.84 | ABCB1 (0.38) | ALDH1A1TLR7HDAC1HDAC8HDAC6 | |
| SCHEMBL10042788 | 0.83 | RAB9A (0.52) | ALDH1A1KDM4EABCB1 | |
| Hydrochloric Acid SCHEMBL20529544 | 0.82 | RAB9A (0.54) | ALDH1A1KDM4EABCB1 | |
| Hydrochloric Acid SCHEMBL20529546 | 0.82 | RAB9A (0.54) | ALDH1A1KDM4EABCB1 | |
| SCHEMBL9415797 | 0.79 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PLA2G4ATLR7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518786-B2 | Third generation tubulysin analogues and process of preparation thereof | Indian Institute of Technology Indore (IN) | 2022-12-06 | — | — | US | disclosed |
| US-20220056079-A1 | THIRD GENERATION TUBULYSIN ANALOGUES AND PROCESS OF PREPARATION THEREOF | Indian Institute of Technology Indore (IN) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518786-B2 | Third generation tubulysin analogues and process of preparation thereof | TEK, VIP, SCTR | L3MBTL1 4150/4885ALDH1A1 4849/4885PLA2G4A 760/4885 |
| US-20220056079-A1 | THIRD GENERATION TUBULYSIN ANALOGUES AND PROCESS OF PREPARATION THEREOF | TEK, VIP, SCTR | L3MBTL1 4150/4885ALDH1A1 4849/4885PLA2G4A 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.