Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905716 | 1.00 | L3MBTL1 (0.53) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL1979608 | 0.83 | L3MBTL1 (0.58) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL17354619 | 0.82 | AR (0.40) | GAAPPARGKDM4ERAB9ANPC1 | |
| SCHEMBL13720426 | 0.81 | L3MBTL1 (0.56) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL29437987 | 0.81 | L3MBTL1 (0.59) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL12593964 | 0.81 | L3MBTL1 (0.59) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL29437991 | 0.81 | L3MBTL1 (0.58) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL1982917 | 0.81 | L3MBTL1 (0.58) | L3MBTL1GAAHSPB1MAPTNPSR1 | |
| SCHEMBL1978329 | 0.81 | KDM4E (0.48) | NPSR1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL17354607 | 0.80 | HSPB1 (0.50) | L3MBTL1GAAHSPB1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | L3MBTL1 2799/4885GAA 3446/4885HSPB1 1810/4885 |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNN3, KCND3, KCNA3 | L3MBTL1 2799/4885GAA 3446/4885HSPB1 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.