Gemilukast

Gemilukast

SCHEMBL29438733

Cc1c(F)cccc1CCCCOc1ccc(C#Cc2ccc(F)c3c(CCCC(=O)O)c(C)n(CCCC(=O)O)c23)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 20/20 1.00
CYSLTR1 Q9Y271 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gemilukast SCHEMBL597344 1.00 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL598642 0.93 CYSLTR2 (1.00) CYSLTR2CYSLTR1
Gemilukast SCHEMBL597425 0.92 CYSLTR2 (0.86) CYSLTR2CYSLTR1
Gemilukast SCHEMBL598116 0.92 CYSLTR2 (0.84) CYSLTR2CYSLTR1
Gemilukast SCHEMBL597080 0.91 CYSLTR2 (0.83) CYSLTR2CYSLTR1
Gemilukast SCHEMBL597081 0.91 CYSLTR2 (0.83) CYSLTR2CYSLTR1
SCHEMBL598035 0.90 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL597067 0.89 CYSLTR2 (0.88) CYSLTR2CYSLTR1
SCHEMBL597788 0.87 CYSLTR2 (0.89) CYSLTR2CYSLTR1
SCHEMBL10143243 0.86 CYSLTR2 (0.76) CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS MODEL MEDICINES INC (US) 2026-05-07 US disclosed
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES MODEL MEDICINES INC (US) 2026-04-16 US disclosed
EP-4359402-B1 IMIDAZOLO INDAZOLE COMPOUNDS AS JAK INHIBITORS THERAVANCE BIOPHARMA R&D IP LLC (US) 2026-03-11 EP disclosed
EP-3985126-B1 NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC STEATOHEPATITIS GENFIT (FR) 2026-03-04 EP disclosed
US-12551475-B2 Methods and compositions for treating RNA viral infections MODEL MEDICINES, INC. (US) 2026-02-17 US disclosed
EP-4355915-B1 METHOD FOR NASH RISK ASSESSMENT IN PATIENTS HAVING A METABOLIC DISORDER GENFIT (FR) 2026-02-04 EP disclosed
EP-4667008-A2 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2025-12-24 EP disclosed
US-20250367229-A1 Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof MITOPOWER LLC (US) 2025-12-04 US disclosed
EP-3684954-B1 NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC FATTY LIVER DISEASES, NON-ALCOHOLIC STEATOHEPATITIS AND/OR LIVER FIBROSIS GENFIT (FR) 2025-11-26 EP disclosed
EP-3612176-B1 COMBINATION COMPRISING THE PPAR AGONIST ELAFIBRANOR AND AN ACETYL-COA CARBOXYLASE (ACC) INHIBITOR SELECTED FROM CP-640186, GEMCABENE, GS-0976 TO TREAT INFLAMMATORY, METABOLIC, FIBROTIC OR CHOLESTATIC DISEASES GENFIT (FR) 2025-09-17 EP disclosed
CN-110461839-B JAK inhibitors containing 4-membered heterocyclic amides 施万生物制药研发IP有限责任公司 2022-08-23 CN disclosed
US-20220241232-A1 METHOD FOR TREATMENT OF AT RISK PATIENTS GENFIT (FR) 2022-08-04 US disclosed
WO-2022159763-A1 SARS-COV-2 THERAPEUTICS MODEL MEDICINES, INC. (US) 2022-07-28 WO disclosed
CN-110382498-B Fused imidazole-piperidine JAK inhibitors 施万生物制药研发IP有限责任公司 2022-07-12 CN disclosed
US-20220162702-A1 DIAGNOSIS OF NON-ALCOHOLIC STEATOHEPATITIS GENFIT (FR) 2022-05-26 US disclosed
EP-3986420-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES Mitopower LLC (US) 2022-04-27 EP disclosed
EP-3985126-A1 NON-INVASIVE DIAGNOSTIC OF NON-ALCOHOLIC STEATOHEPATITIS Genfit (FR) 2022-04-20 EP disclosed
EP-3980070-A1 METHOD FOR TREATMENT OF AT RISK PATIENTS Genfit (FR) 2022-04-13 EP disclosed
US-11286274-B2 Nicotinamide riboside derivatives and their uses MITOPOWER LLC (US) 2022-03-29 US disclosed
US-20220062314-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES MitoPower, LLC (US) 2022-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220062314-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES NADK, NNT, NAMPT CYSLTR2 4170/4885CYSLTR1 3903/4885
US-11286274-B2 Nicotinamide riboside derivatives and their uses NME4, NADK, NQO1 CYSLTR2 3450/4885CYSLTR1 3112/4885
US-12551475-B2 Methods and compositions for treating RNA viral infections SARS1, EIF2AK2, SNRPE CYSLTR2 1660/4885CYSLTR1 1868/4885
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES ESR1, VDR, POLL CYSLTR2 3109/4885CYSLTR1 3162/4885
US-20220241232-A1 METHOD FOR TREATMENT OF AT RISK PATIENTS SLC10A1, CPT1A, FABP1 CYSLTR2 188/4885CYSLTR1 450/4885
US-20250367229-A1 Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof NQO1, DOHH, DHODH CYSLTR2 3184/4885CYSLTR1 3146/4885
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS SARS1, NSUN2, NSUN3 CYSLTR2 1645/4885CYSLTR1 2482/4885
US-20220162702-A1 DIAGNOSIS OF NON-ALCOHOLIC STEATOHEPATITIS FABP1, SLC10A1, FABP2 CYSLTR2 892/4885CYSLTR1 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.