SCHEMBL29439087

SCHEMBL29439087

CC(C)CC(NC(=O)C(N)CCCCN)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C)C(=O)NC(C(=O)NCC(=O)NC(C(=O)O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 3/20 0.47
▸ PRSS1 P07477 1/20 0.43
▸ BACE1 P56817 5/20 0.41
▸ CTSD P07339 3/20 0.41
▸ PCSK6 P29122 1/20 0.41
▸ TFPI P10646 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30629771 0.87 NPY4R (0.45) FURINBACE1CTSDPCSK6
SCHEMBL29912721 0.86 FURIN (0.47) FURINPRSS1BACE1CTSD
SCHEMBL30824280 0.86 BACE1 (0.48) FURINPRSS1BACE1CTSD
SCHEMBL31299908 0.84 TFPI (0.46) FURINBACE1TFPI
SCHEMBL30531774 0.84 GSR (0.42) FURINPRSS1BACE1CTSD
SCHEMBL28081113 0.84 BACE1 (0.49) FURINBACE1CTSD
SCHEMBL31299907 0.83 OPRM1 (0.46) FURINBACE1CTSDTFPI
SCHEMBL28081212 0.83 EGFR (0.49) FURINBACE1CTSDTFPI
SCHEMBL30532205 0.83 FURIN (0.49) FURINPRSS1BACE1CTSD
SCHEMBL29531524 0.82 NTSR2 (0.45) FURINBACE1CTSDPCSK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731674-A2 COMPOSITIONS AND METHODS FOR BINDING TO COVALENT PEPTIDE CONJUGATES New York University (US) 2026-04-29 — — EP claimed
US-20260109958-A1 T-Cell Modulatory Polypeptides and Methods of Use Thereof CUE BIOPHARMA INC (US) 2026-04-23 — — US claimed
EP-4656655-A1 TCR MOLECULES TARGETING KRAS MUTATION, CELLS AND USE OF TCR MOLECULES AND CELLS Beijing DCTY Biotech Co., Ltd. (CN) 2025-12-03 — — EP claimed
US-20250353912-A1 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES UNIV NEW YORK (US) 2025-11-20 — — US claimed
WO-2025226775-A2 COMPOSITIONS AND METHODS FOR BINDING TO COVALENT PEPTIDE CONJUGATES NEW YORK UNIVERSITY (US) 2025-10-30 — — WO claimed
US-20250269002-A1 CTA VACCINE CASSETTES GRITSTONE BIO INC (US) 2025-08-28 — — US claimed
EP-4565264-A2 CTA VACCINE CASSETTES Gritstone bio, Inc. (US) 2025-06-11 — — EP claimed
EP-4543931-A2 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES New York University (US) 2025-04-30 — — EP claimed
WO-2024031027-A9 CTA VACCINE CASSETTES GRITSTONE BIO, INC. (US) 2025-04-24 — — WO claimed
CN-119866347-A Compositions and methods comprising antibodies conjugated to covalent peptide conjugates 纽约大学 2025-04-22 — — CN claimed
EP-4106785-A1 MOLECULES TARGETING MUTANT RAS PROTEIN Aelin Therapeutics (BE) 2022-12-28 — — EP claimed
CN-115175934-A Antigen binding proteins targeting consensus neoantigens 磨石生物公司 2022-10-11 — — CN claimed
WO-2022197971-A1 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2022-09-22 — — WO claimed
EP-4058484-A2 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS Gritstone bio, Inc. (US) 2022-09-21 — — EP claimed
EP-4030897-A1 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF Cue Biopharma, Inc. (US) 2022-07-27 — — EP claimed
WO-2022099156-A2 T-CELL MODULATORY POLYPEPTIDES WITH CONJUGATION SITES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2022-05-12 — — WO claimed
WO-2022099157-A1 ANTIGEN PRESENTING POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2022-05-12 — — WO claimed
US-20220143063-A1 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. 2022-05-12 — — US claimed
CN-114423284-A T cell modulating polypeptides and methods of use thereof 库尔生物制药有限公司 2022-04-29 — — CN claimed
CN-114026116-A RAS neoantigen specific binding proteins and uses thereof 弗雷德哈钦森癌症研究中心 2022-02-08 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143063-A1 T-CELL MODULATORY POLYPEPTIDES AND METHODS OF USE THEREOF MICA, CD74, HLA-DRB1 FURIN 420/4885PRSS1 196/4885BACE1 547/4885
US-20260109958-A1 T-Cell Modulatory Polypeptides and Methods of Use Thereof CD74, KRAS, MICA FURIN 777/4885PRSS1 1590/4885BACE1 992/4885
US-20250353912-A1 COMPOSITIONS AND METHODS COMPRISING ANTIBODIES THAT BIND TO COVALENT PEPTIDE CONJUGATES MICA, CD74, HLA-DRB1 FURIN 556/4885PRSS1 3160/4885BACE1 1889/4885
US-20250269002-A1 CTA VACCINE CASSETTES KRAS, TP53, TSG101 FURIN 264/4885PRSS1 795/4885BACE1 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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