SCHEMBL29439292

SCHEMBL29439292

NC[C@H](O)CC[C@H](NC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 3/20 0.43
▸ CA1 P00915 3/20 0.43
▸ CA2 P00918 3/20 0.43
▸ CA9 Q16790 3/20 0.43
▸ PYGB P11216 7/20 0.43
▸ GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26135776 1.00 CA12 (0.43) CA12CA1CA2CA9PYGB
SCHEMBL4292200 1.00 CA12 (0.43) CA12CA1CA2CA9PYGB
SCHEMBL31150424 1.00 CA12 (0.43) CA12CA1CA2CA9PYGB
SCHEMBL20265935 1.00 CA12 (0.43) CA12CA1CA2CA9PYGB
SCHEMBL28448246 0.83 CA12 (0.44) CA12CA1CA2CA9PYGB
SCHEMBL28444663 0.83 CA12 (0.44) CA12CA1CA2CA9PYGB
SCHEMBL734876 0.83 CA12 (0.44) CA12CA1CA2CA9PYGB
SCHEMBL28448523 0.83 CA12 (0.44) CA12CA1CA2CA9PYGB
SCHEMBL9346601 0.81 CA12 (0.42) CA12CA1CA2CA9PYGB
SCHEMBL28732847 0.81 PYGB (0.48) CA12CA1CA2CA9PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4010007-B1 PRODUCTION OF MHC II/CII COMPLEXES FRAUNHOFER GES FORSCHUNG (DE) 2023-11-15 — — EP claimed
US-20220288177-A1 PRODUCTION OF MHC II/CII COMPLEXES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-15 — — US claimed
EP-4010006-A1 HLA-DR/CII PEPTIDE COMPLEXES FOR TREATING ARTHRITIS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-06-15 — — EP claimed
EP-4010007-A1 PRODUCTION OF MHC II/CII COMPLEXES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-06-15 — — EP claimed
CN-114206945-A Production of MHC II/CII peptide complexes 弗劳恩霍夫应用研究促进协会 2022-03-18 — — CN claimed
US-12622946-B2 HLA-DR/CII peptide complexes for treating arthritis Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2026-05-12 — — US disclosed
US-20250207168-A1 PRODUCTION CELLS HOFFMANN-LA ROCHE INC. (US) 2025-06-26 — — US disclosed
EP-4532526-A1 IMPROVED PRODUCTION CELLS F. Hoffmann-La Roche AG (CH) 2025-04-09 — — EP disclosed
CN-119630690-A Improved producer cells 豪夫迈·罗氏有限公司 2025-03-14 — — CN disclosed
US-20250032591-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING CONNECTIVE TISSUE CONDITIONS WITH COLLAGEN POLYPEPTIDES GELTOR, INC. 2025-01-30 — — US disclosed
US-20240415757-A1 ANIMAL-FREE COSMETIC COLLAGENS GELTOR, INC. 2024-12-19 — — US disclosed
CN-118750607-A HLA-DR/CII peptide complexes for the treatment of arthritis 弗劳恩霍夫应用研究促进协会 2024-10-11 — — CN disclosed
US-20220332775-A1 ANIMAL-FREE DIETARY COLLAGEN GELTOR, INC. 2022-10-20 — — US disclosed
US-20220288177-A1 PRODUCTION OF MHC II/CII COMPLEXES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-15 — — US disclosed
US-20220280599-A1 HLA-DR/CII PEPTIDE COMPLEXES FOR TREATING ARTHRITIS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-09-08 — — US disclosed
EP-4010006-A1 HLA-DR/CII PEPTIDE COMPLEXES FOR TREATING ARTHRITIS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-06-15 — — EP disclosed
EP-4010007-A1 PRODUCTION OF MHC II/CII COMPLEXES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-06-15 — — EP disclosed
US-11332505-B2 Animal-free dietary collagen GELTOR, INC. (US) 2022-05-17 — — US disclosed
CN-114302743-A HLA-DR/CII peptide complexes for the treatment of arthritis 弗劳恩霍夫应用研究促进协会 2022-04-08 — — CN disclosed
CN-114206945-A Production of MHC II/CII peptide complexes 弗劳恩霍夫应用研究促进协会 2022-03-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288177-A1 PRODUCTION OF MHC II/CII COMPLEXES HLA-DRB1, MICA, CD74 CA12 556/4885CA1 1508/4885CA2 3505/4885
US-12622946-B2 HLA-DR/CII peptide complexes for treating arthritis HLA-DRB1, MICA, CD74 CA12 2982/4885CA1 2768/4885CA2 3479/4885
US-20220280599-A1 HLA-DR/CII PEPTIDE COMPLEXES FOR TREATING ARTHRITIS HLA-DRB1, CD74, HLA-C CA12 1416/4885CA1 1558/4885CA2 2706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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