Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676819 | 1.00 | LMNA (0.45) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL24894558 | 0.89 | LMNA (0.40) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL23969660 | 0.86 | ALDH1A1 (0.43) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL23534358 | 0.84 | ALDH1A1 (0.44) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL27695116 | 0.83 | ALDH1A1 (0.45) | LMNAALDH1A1CYP1A2CYP2C9MAPT | |
| SCHEMBL23969551 | 0.83 | LMNA (0.44) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL30731578 | 0.83 | LMNA (0.44) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL13706557 | 0.83 | ALDH1A1 (0.44) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL2177419 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9MAPTGAA | |
| SCHEMBL31463754 | 0.82 | LMNA (0.40) | LMNAALDH1A1CYP1A2CYP2C9PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665454-A1 | IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| WO-2024173173-A1 | IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |