Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22715552 | 1.00 | P2RX3 (0.37) | P2RX3P2RX2PIK3CDTRPV1PIK3CA | |
| SCHEMBL22715950 | 0.85 | PIK3CD (0.37) | P2RX3P2RX2PIK3CDPIK3CA | |
| SCHEMBL29439836 | 0.85 | PIK3CD (0.37) | P2RX3P2RX2PIK3CDPIK3CA | |
| SCHEMBL22715558 | 0.85 | PIK3CD (0.37) | P2RX3P2RX2PIK3CDPIK3CA | |
| SCHEMBL29439669 | 0.85 | PIK3CD (0.37) | P2RX3P2RX2PIK3CDPIK3CA | |
| SCHEMBL23870044 | 0.78 | IP6K1 (0.39) | PIK3CD | |
| SCHEMBL29439678 | 0.78 | IP6K1 (0.39) | PIK3CD | |
| SCHEMBL2849692 | 0.72 | GRIN2D (0.52) | P2RX3PIK3CDPIK3CA | |
| SCHEMBL8088154 | 0.72 | KDM4E (0.47) | P2RX3P2RX2 | |
| SCHEMBL2849660 | 0.71 | TRPV1 (0.53) | P2RX3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |