Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ADK | P55263 | 8/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22715806 | 1.00 | PIK3CG (0.61) | PIK3CGPIK3CAPIK3CBHDAC6ADK | |
| SCHEMBL3799709 | 0.82 | PIK3CG (0.62) | PIK3CGPIK3CAPIK3CBHDAC6ADK | |
| SCHEMBL11446157 | 0.75 | MAP4K4 (0.61) | PIK3CGADKMAP4K4 | |
| SCHEMBL11445170 | 0.75 | PIK3CG (0.61) | PIK3CGPIK3CAPIK3CBHDAC6ADK | |
| SCHEMBL3766438 | 0.74 | PIK3CG (0.63) | PIK3CGADKMAP4K4HPGD | |
| SCHEMBL11446163 | 0.73 | ADK (0.67) | PIK3CGADKHPGD | |
| SCHEMBL8147564 | 0.72 | ADK (0.68) | ADKALDH1A1MAPTHPGD | |
| SCHEMBL8139237 | 0.71 | ADK (0.76) | ADKALDH1A1MAPTHPGD | |
| SCHEMBL17027901 | 0.71 | IDO1 (0.58) | ALDH1A1MAPTHPGDHK1RAB9A | |
| SCHEMBL14738663 | 0.71 | BIRC5 (0.45) | PIK3CGALDH1A1MAPTHPGDHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |