Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.61 |
| ▸ | ADK | P55263 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467366 | 0.83 | BCHE (0.53) | PIK3CGADKBCHEACHEPIK3CA | |
| SCHEMBL11446157 | 0.83 | MAP4K4 (0.61) | PIK3CGADKATRMAP4K4 | |
| SCHEMBL11453447 | 0.82 | ADK (0.72) | PIK3CGADKPIK3CAPIK3CBPIK3CD | |
| SCHEMBL11446163 | 0.82 | ADK (0.67) | PIK3CGADKKDM4EPOLBPPARG | |
| SCHEMBL22744042 | 0.78 | PIK3CG (0.56) | PIK3CGBCHEACHEPIK3CAPIK3CB | |
| SCHEMBL3745255 | 0.76 | PIK3CG (1.00) | PIK3CGADKPIK3CAPIK3CBHDAC6 | |
| SCHEMBL22744495 | 0.76 | MAP4K4 (0.49) | PIK3CGPIK3CAPIK3CBPIK3CDPRKDC | |
| SCHEMBL18135276 | 0.76 | MAP4K4 (0.72) | MAP4K4 | |
| SCHEMBL22715806 | 0.75 | PIK3CG (0.61) | PIK3CGADKPIK3CAPIK3CBMAP4K4 | |
| SCHEMBL29439870 | 0.75 | PIK3CG (0.61) | PIK3CGADKPIK3CAPIK3CBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187307-A | 4-AMINOPTERIDINES | ABBOTT LABORATORIES (US) | 1980-02-05 | — | — | US | disclosed |