Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 4/20 | 0.49 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.48 |
| ▸ | CALCR | P30988 | 2/20 | 0.48 |
| ▸ | CALCA | P06881 | 1/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.47 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440833 | 0.95 | OPRM1 (0.54) | OPRM1OPRK1APLNRTFPIRAMP3 | |
| SCHEMBL31433260 | 0.85 | RAMP3 (0.55) | APLNRRAMP3CALCRNMUR2NMUR1 | |
| SCHEMBL31433268 | 0.85 | RAMP3 (0.55) | APLNRRAMP3CALCRNMUR2NMUR1 | |
| SCHEMBL25475911 | 0.84 | APLNR (0.50) | OPRM1OPRK1APLNRTFPIRAMP3 | |
| SCHEMBL29568631 | 0.84 | RAMP3 (0.50) | OPRM1OPRK1RAMP3CALCRNMUR2 | |
| SCHEMBL29568528 | 0.84 | RAMP3 (0.50) | OPRM1OPRK1RAMP3CALCRNMUR2 | |
| SCHEMBL15182357 | 0.84 | OPRM1 (0.64) | OPRM1OPRK1APLNROPRD1 | |
| SCHEMBL29568732 | 0.84 | NMUR2 (0.47) | OPRM1OPRK1APLNRRAMP3CALCR | |
| SCHEMBL31433337 | 0.84 | RAMP3 (0.55) | APLNRRAMP3CALCRIL23R | |
| SCHEMBL29569305 | 0.84 | RAMP3 (0.50) | OPRM1OPRK1RAMP3CALCRNMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110193087-B | Tumor microenvironment response type diagnosis and treatment integrated nanoprobe and preparation method thereof | 山西医科大学 | 2022-02-08 | — | — | CN | claimed |
| CN-110193087-B | Tumor microenvironment response type diagnosis and treatment integrated nanoprobe and preparation method thereof | 山西医科大学 | 2022-02-08 | — | — | CN | disclosed |