Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 14/20 | 0.70 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22208321 | 1.00 | SQOR (0.70) | SQORIKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL22208318 | 0.83 | SQOR (1.00) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL29442359 | 0.83 | SQOR (1.00) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL29442258 | 0.83 | SQOR (0.81) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL22208456 | 0.83 | SQOR (0.81) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL22208274 | 0.81 | SQOR (0.78) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL29442279 | 0.81 | SQOR (0.78) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL22208210 | 0.81 | SQOR (0.78) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL22215864 | 0.80 | SQOR (1.00) | SQORKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL22208298 | 0.78 | SQOR (0.82) | SQORKDM4EALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | DREXEL UNIVERSITY | 2022-03-31 | — | — | US | claimed |
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | DREXEL UNIVERSITY | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | SQOR, QSOX1, KEAP1 | SQOR 1/4885IKBKB 241/4885KDM4E 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.