Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15154729 | 0.81 | RIPK1 (0.46) | NPC1LMNANPSR1ALDH1A1 | |
| SCHEMBL2598872 | 0.81 | RIPK1 (0.46) | NPC1LMNANPSR1ALDH1A1 | |
| SCHEMBL2944251 | 0.81 | NPC1 (0.50) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL1865291 | 0.78 | HSD11B1 (0.57) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL1951112 | 0.78 | HSD11B1 (0.57) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL1951111 | 0.78 | HSD11B1 (0.57) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL1865290 | 0.78 | HSD11B1 (0.57) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL31472401 | 0.77 | ATAD2 (0.42) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL21491336 | 0.77 | ATAD2 (0.42) | NPC1UCHL1USP30RAB9ALMNA | |
| SCHEMBL31472353 | 0.77 | ATAD2 (0.42) | NPC1UCHL1USP30RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856096-B1 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL MYERS SQUIBB CO (US) | 2010-09-01 | — | — | EP | disclosed |
| EP-1856096-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Bristol-Myers Squibb Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |