Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.86 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.86 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.86 |
| ▸ | XDH | P47989 | 3/20 | 0.86 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.86 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.86 |
| ▸ | CA12 | O43570 | 2/20 | 0.86 |
| ▸ | CA2 | P00918 | 2/20 | 0.86 |
| ▸ | CA4 | P22748 | 2/20 | 0.86 |
| ▸ | PPARG | P37231 | 2/20 | 0.86 |
| ▸ | CA7 | P43166 | 2/20 | 0.86 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isorhamnetin SCHEMBL29390102 | 0.93 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL30385934 | 0.93 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL19235 | 0.93 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29377152 | 0.93 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL31408172 | 0.93 | NOX4 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29929374 | 0.93 | NOX4 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL890990 | 0.93 | NOX4 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL3715283 | 0.89 | MEN1 (0.93) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL28182051 | 0.89 | MEN1 (0.93) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL17620251 | 0.89 | ABCG2 (0.77) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114184727-B | Identification method of three medicinal materials from gleditsia sinensis and application thereof | 天津中医药大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114184727-A | Identification method of three medicinal materials derived from gleditschia horrida and application thereof | 天津中医药大学 | 2022-03-15 | — | — | CN | disclosed |