SCHEMBL890990

SCHEMBL890990

COc1cc(O)cc2oc(-c3ccc(O)c(O)c3)c(O)c(=O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX4 Q9NPH5 2/20 1.00
▸ MEN1 O00255 7/20 0.74
▸ KMT2A Q03164 7/20 0.74
▸ CYP1A2 P05177 5/20 0.74
▸ CYP1A1 P04798 4/20 0.74
▸ CYP1B1 Q16678 4/20 0.74
▸ IPMK Q8NFU5 3/20 0.74
▸ IP6K2 Q9UHH9 3/20 0.74
▸ XDH P47989 3/20 0.74
▸ CA12 O43570 2/20 0.74
▸ CA2 P00918 2/20 0.74
▸ CA4 P22748 2/20 0.74
▸ PPARG P37231 2/20 0.74
▸ CA7 P43166 2/20 0.74
▸ KDM4E B2RXH2 6/20 0.72
▸ HSD17B10 Q99714 5/20 0.72
▸ CYP3A4 P08684 5/20 0.72
▸ MAPT P10636 5/20 0.72
▸ RECQL P46063 4/20 0.72
▸ LMNA P02545 4/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31408172 1.00 NOX4 (1.00) NOX4MEN1KMT2ACYP1A2CYP1A1
SCHEMBL29929374 1.00 NOX4 (1.00) NOX4MEN1KMT2ACYP1A2CYP1A1
SCHEMBL29442903 0.93 MEN1 (0.86) NOX4MEN1KMT2ACYP1A2CYP1A1
SCHEMBL27693769 0.90 NOX4 (0.81) NOX4MEN1KMT2ACYP1A2CYP1A1
Isorhamnetin SCHEMBL3715283 0.89 MEN1 (0.93) NOX4MEN1KMT2ACYP1A2CYP1A1
SCHEMBL31304741 0.89 POLB (0.82) NOX4MEN1KMT2AXDHKDM4E
SCHEMBL30284949 0.89 POLB (0.82) NOX4MEN1KMT2AXDHKDM4E
SCHEMBL11149169 0.89 POLB (0.82) NOX4MEN1KMT2AXDHKDM4E
SCHEMBL26936149 0.89 KDM4E (0.82) NOX4MEN1KMT2ACYP1A2CYP1A1
SCHEMBL15635189 0.88 NOX4 (0.79) NOX4MEN1KMT2ACYP1A2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 — — EP claimed
WO-2025235852-A1 FLAVONOID COMPOSITIONS AND METHODS OF USE SYNGENTA CROP PROTECTION AG (CH) 2025-11-13 — — WO claimed
WO-2025038482-A2 USE OF FISETIN FOR REDUCING THE INCIDENCE OF ATRIAL FIBRILLATION RHODE ISLAND HOSPITAL (US) 2025-02-20 — — WO claimed
US-20250009892-A1 DELIVERY SYSTEMS AND METHODS FOR REACTIVE HYDROXYL-CONTAINING COMPOUNDS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2025-01-09 — — US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
US-11560342-B2 Bacillus isolates and uses thereof MONSANTO TECHNOLOGY, LLC (US) 2023-01-24 — — US claimed
WO-2022194862-A1 METHOD FOR PREDICTING THE LIKELIHOOD OF PREGNANCY IN FEMALE MAMMALS WHICH EXPERIENCE AN ESTROUS CYCLE BREEDSENSE AS (NO) 2022-09-22 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
EP-2755499-A1 QUERCETIN FOR BROWNING FOOD SURFACES Nestec S.A. (CH) 2014-07-23 — — EP claimed
EP-2736484-A1 BOTANICAL ANTIOXIDANT COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF US CosmeceuTechs LLC (US) 2014-06-04 — — EP claimed
US-8642087-B1 Compounds and methods for reducing oxidative stress UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2014-02-04 — — US claimed
EP-2665467-A2 FLAVONOL COMPOSITIONS Ono, Mitsunori (US) 2013-11-27 — — EP claimed
WO-2013037603-A1 QUERCETIN FOR BROWNING FOOD SURFACES NESTEC S.A. (CH) 2013-03-21 — — WO claimed
WO-2013016257-A1 BOTANICAL ANTIOXIDANT COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF US COSMECEU TECHS LLC (US) 2013-01-31 — — WO claimed
US-20120208118-A1 RESIN COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2012-08-16 — — US claimed
WO-2012099930-A2 FLAVONOL COMPOSITIONS ONO MITSUNORI (US) 2012-07-26 — — WO claimed
US-20120183587-A1 FLAVONOL COMPOSITIONS LINES, THOMAS CHRISTIAN (CH) 2012-07-19 — — US claimed
CN-101119719-A The use of flavonol and flavonol glycosides for stimulating growth of renal tubular epithelial cells to secrete the kidney secreting bone growth factor MIAN LONG (US) 2008-02-06 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB NOX4 3675/4885MEN1 1711/4885KMT2A 4742/4885
US-20120183587-A1 FLAVONOL COMPOSITIONS CYP2F1, F3, TEAD3 NOX4 3973/4885MEN1 2383/4885KMT2A 2991/4885
US-11560342-B2 Bacillus isolates and uses thereof BLVRB, BROX, GLB1 NOX4 3145/4885MEN1 3424/4885KMT2A 4261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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