SCHEMBL29443911

SCHEMBL29443911

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)O)C(C)C)[C@@H](C)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 13/20 0.62
▸ ECE1 P42892 1/20 0.61
▸ MUS81 Q96NY9 1/20 0.61
▸ OPRM1 P35372 4/20 0.61
▸ OPRD1 P41143 4/20 0.61
▸ KISS1R Q969F8 1/20 0.59
▸ OPRK1 P41145 1/20 0.57
▸ NPBWR1 P48145 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443914 0.98 GLP1R (0.61) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690352 0.98 GLP1R (0.62) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690338 0.98 GLP1R (0.62) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690385 0.97 OPRM1 (0.61) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690390 0.96 GLP1R (0.61) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL29443919 0.95 OPRM1 (0.63) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690322 0.94 OPRM1 (0.63) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690379 0.93 OPRD1 (0.60) GLP1RECE1MUS81OPRM1OPRD1
SCHEMBL30690372 0.93 GLP1R (0.66) GLP1RECE1MUS81OPRD1
SCHEMBL30690358 0.93 GLP1R (0.66) GLP1RECE1MUS81OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11806365-B2 Modified T lymphocytes comprising a CD52 antibody-inducible caspase and methods of apoptosis CELGENE CORPORATION (US) 2023-11-07 — — US disclosed
US-20220324991-A1 BCMA-BINDING ANTIBODIES AND USES THEREOF CELGENE CORPORATION 2022-10-13 — — US disclosed
US-11401336-B2 BCMA-binding antibodies and uses thereof CELGENE CORPORATION (US) 2022-08-02 — — US disclosed
US-20220106404-A1 CHIMERIC ANTIGEN RECEPTORS CELGENE CORPORATION 2022-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324991-A1 BCMA-BINDING ANTIBODIES AND USES THEREOF CD79B, BCL6, CD22 GLP1R 4654/4885ECE1 2117/4885MUS81 2045/4885
US-11401336-B2 BCMA-binding antibodies and uses thereof CD79B, BCL6, CD22 GLP1R 4654/4885ECE1 2117/4885MUS81 2045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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