SCHEMBL29443919

SCHEMBL29443919

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)O)C(C)C)C(C)C)C(C)C)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.63
▸ OPRD1 P41143 2/20 0.63
▸ KISS1R Q969F8 6/20 0.60
▸ GLP1R P43220 8/20 0.60
▸ ECE1 P42892 1/20 0.60
▸ MUS81 Q96NY9 1/20 0.60
▸ NPBWR1 P48145 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30690322 0.98 OPRM1 (0.63) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL30690379 0.98 OPRD1 (0.60) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL29443914 0.96 GLP1R (0.61) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL29443911 0.95 GLP1R (0.62) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL30690385 0.94 OPRM1 (0.61) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL30690390 0.94 GLP1R (0.61) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL30690338 0.93 GLP1R (0.62) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL30690352 0.93 GLP1R (0.62) OPRM1OPRD1KISS1RGLP1RECE1
SCHEMBL30690372 0.92 GLP1R (0.66) OPRD1GLP1RECE1MUS81
SCHEMBL30690358 0.92 GLP1R (0.66) OPRD1GLP1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11806365-B2 Modified T lymphocytes comprising a CD52 antibody-inducible caspase and methods of apoptosis CELGENE CORPORATION (US) 2023-11-07 — — US disclosed
US-20220324991-A1 BCMA-BINDING ANTIBODIES AND USES THEREOF CELGENE CORPORATION 2022-10-13 — — US disclosed
US-11401336-B2 BCMA-binding antibodies and uses thereof CELGENE CORPORATION (US) 2022-08-02 — — US disclosed
US-20220106404-A1 CHIMERIC ANTIGEN RECEPTORS CELGENE CORPORATION 2022-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324991-A1 BCMA-BINDING ANTIBODIES AND USES THEREOF CD79B, BCL6, CD22 OPRM1 2539/4885OPRD1 4280/4885KISS1R 4249/4885
US-11401336-B2 BCMA-binding antibodies and uses thereof CD79B, BCL6, CD22 OPRM1 2539/4885OPRD1 4280/4885KISS1R 4249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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