Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.92 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.92 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.92 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.92 |
| ▸ | SRC | P12931 | 2/20 | 0.92 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.92 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.92 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.92 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.86 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.86 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.86 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.86 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.86 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.85 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.85 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.85 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.85 |
| ▸ | LDHA | P00338 | 1/20 | 0.85 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Diphosphate SCHEMBL29979301 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL24103 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL29358868 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL18785159 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL14613190 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL18089780 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL12789537 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL195251 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL135142 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC | |
| Adenosine Diphosphate SCHEMBL14180716 | 1.00 | P2RY1 (0.92) | P2RY1P2RY2P2RX1P2RX3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124511-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | TIANJIN HONGKE BAISHI QIXIN VENTURE CAPITAL PARTNERSHIP (LIMITED PARTNERSHIP) (CN) | 2024-04-18 | — | — | US | disclosed |
| US-11840551-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2023-12-12 | — | — | US | disclosed |
| US-11773131-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2023-10-03 | — | — | US | disclosed |
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) | 2022-06-09 | — | — | US | disclosed |
| CN-114025771-A | Glycerol-mannose-heptose ADP derivatives for modulating immune response | 上海药苑生物科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | GALK1, PHKA1, PGK1 | P2RY1 135/4885P2RY2 254/4885P2RX1 355/4885 |
| US-11840551-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | PHKA1, PHKA2, PRKCA | P2RY1 561/4885P2RY2 796/4885P2RX1 885/4885 |
| US-20240124511-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | PHKA1, PHKA2, PRKCA | P2RY1 561/4885P2RY2 796/4885P2RX1 885/4885 |
| US-11773131-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | PHKA1, PHKA2, PRKCA | P2RY1 561/4885P2RY2 796/4885P2RX1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.