Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210975 | 1.00 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL19210856 | 1.00 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29444533 | 0.78 | CES1 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL19210912 | 0.78 | CES1 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL32662403 | 0.74 | CA1 (0.32) | — | |
| SCHEMBL5988227 | 0.69 | CES1 (0.44) | — | |
| SCHEMBL5739112 | 0.68 | CES1 (0.50) | — | |
| SCHEMBL5739017 | 0.68 | CA1 (0.41) | — | |
| SCHEMBL24399769 | 0.67 | TGM2 (0.43) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL5740135 | 0.66 | CES1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884096-B | Spiroindolinones as DDR1 inhibitors | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | disclosed |