SCHEMBL29444572

SCHEMBL29444572

C[C@H](C(=O)O)N(C)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.46
FABP7 O15540 2/20 0.46
KMT2A Q03164 2/20 0.44
CASP3 P42574 2/20 0.42
EPHX2 P34913 1/20 0.41
MDM4 O15151 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17810782 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL29908645 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL30510263 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL29855002 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL16095352 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL29378715 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL956106 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL120099 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL120596 1.00 FABP5 (0.46) FABP5FABP7KMT2ACASP3EPHX2
SCHEMBL30522085 0.95 FABP5 (0.43) FABP5FABP7KMT2ACASP3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631955-A1 PURIFICATION METHOD AND PRODUCTION METHOD OF CYCLIC PEPTIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-15 EP disclosed
US-20250302912-A1 COMPOSITION INCLUDING PEPTIDE COMPOUND AND SURFACTANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-02 US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-20250276995-A1 PRODUCTION METHOD FOR PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-04 US disclosed
EP-4609875-A2 COMPOSITION CONTAINING PEPTIDE COMPOUND AND SURFACTANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-03 EP disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
EP-4166133-B1 COMPOSITION CONTAINING PEPTIDE COMPOUND AND SURFACTANT CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-23 EP disclosed
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-17 US disclosed
EP-4578868-A1 CYCLIC PEPTIDE OR SALT THEREOF, AND MDMX INHIBITOR FUJIFILM Corporation (JP) 2025-07-02 EP disclosed
WO-2023063376-A1 COMPOSITION INCLUDING PEPTIDE COMPOUND AND SURFACTANT 中外製薬株式会社 2023-04-20 WO disclosed
EP-4166133-A1 COMPOSITION CONTAINING PEPTIDE COMPOUND AND SURFACTANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-04-19 EP disclosed
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-30 US disclosed
WO-2023288213-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-01-19 WO disclosed
CN-109134610-B Peptide compound, application thereof and composition containing peptide compound 尚华医药科技(江西)有限公司 2022-07-08 CN disclosed
CN-111018992-B Compounds and methods for treatment of Trop2 positive diseases 百奥泰生物制药股份有限公司 2022-06-24 CN disclosed
CN-111087471-B Compounds and methods for treatment of Trop2 positive diseases 百奥泰生物制药股份有限公司 2022-06-14 CN disclosed
US-20220125891-A1 METHOD FOR TREATING AND/OR PREVENTING REGNASE-1-RELATED DISEASE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-04-28 US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 EP disclosed
CN-112159462-B Coibatide A derivative and application thereof 深圳先进技术研究院 2022-03-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS FABP5 4631/4885FABP7 4721/4885KMT2A 1250/4885
US-20250276995-A1 PRODUCTION METHOD FOR PEPTIDE COMPOUND VIP, IAPP, QPCT FABP5 1731/4885FABP7 1335/4885KMT2A 2337/4885
US-20250230193-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS KRAS, HRAS, NRAS FABP5 4631/4885FABP7 4721/4885KMT2A 1250/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS FABP5 4094/4885FABP7 4602/4885KMT2A 3145/4885
US-20250302912-A1 COMPOSITION INCLUDING PEPTIDE COMPOUND AND SURFACTANT PCTP, CETP, PLTP FABP5 265/4885FABP7 645/4885KMT2A 4487/4885
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF VIP, DNPEP, HM13 FABP5 1090/4885FABP7 572/4885KMT2A 3453/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R FABP5 2565/4885FABP7 3166/4885KMT2A 4608/4885
US-20220125891-A1 METHOD FOR TREATING AND/OR PREVENTING REGNASE-1-RELATED DISEASE RNASE1, IRAK1, SERBP1 FABP5 3064/4885FABP7 3996/4885KMT2A 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.