Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
| ▸ | CHAT | P28329 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545113 | 1.00 | NFE2L2 (0.53) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL7545111 | 1.00 | NFE2L2 (0.53) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL15447625 | 0.87 | RELA (0.47) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL11698753 | 0.86 | NFE2L2 (0.47) | NFE2L2RELACYP26A1CYP26B1KDM4E | |
| SCHEMBL8099032 | 0.85 | TTR (0.48) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL13636760 | 0.83 | NFE2L2 (0.50) | NFE2L2CYP19A1RELACYP26A1CYP26B1 | |
| SCHEMBL29355253 | 0.83 | RXRA (0.60) | NFE2L2TTRCYP26A1CYP26B1HPGD | |
| SCHEMBL27763816 | 0.82 | NFE2L2 (0.43) | NFE2L2CYP26A1CYP26B1TRPV1HDAC4 | |
| SCHEMBL2748308 | 0.81 | CYP1A2 (0.52) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL6546384 | 0.80 | CYP1A2 (0.55) | NFE2L2CYP19A1MAOAMAOBRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195610-B | Synthesis method of E-type internal olefin compound | 海南大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-114195610-A | Synthetic method of E-type internal olefin compound | 海南大学 | 2022-03-18 | — | — | CN | disclosed |