Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.68 |
| ▸ | MLNR | O43193 | 1/20 | 0.68 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | MC4R | P32245 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742809 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL23522272 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL30788071 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL21731285 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL22669413 | 0.85 | SLC6A2 (0.66) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL21722773 | 0.82 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL29447446 | 0.82 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL21722774 | 0.82 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL21731324 | 0.82 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F | |
| SCHEMBL29447452 | 0.82 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MLNRCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570643-B2 | 3-aryloxy-3-five-membered heteroaryl propylamine compound, and crystal form and use thereof | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2026-03-10 | — | — | US | disclosed |
| CN-114206859-B | 3-Aryloxy-3-five-membered heteroaryl-propylamine compound, and crystal forms and application thereof | 上海璃道医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112566909-B | 3-aryloxy-3-five-membered heteroaryl-propylamine compound and application thereof | 上海璃道医药科技有限公司 | 2023-01-03 | — | — | CN | disclosed |
| US-20220213075-A1 | 3-ARYLOXY-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND, AND CRYSTAL FORM AND USE THEREOF | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2022-07-07 | — | — | US | disclosed |
| CN-114206859-A | 3-aryloxy-3-pentabasic heteroaryl-propylamine compound and crystal form and application thereof | 上海璃道医药科技有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213075-A1 | 3-ARYLOXY-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND, AND CRYSTAL FORM AND USE THEREOF | TRPM5, TRPV5, TRPM7 | SLC6A4 109/4885SLC6A3 76/4885SLC6A2 353/4885 |
| US-12570643-B2 | 3-aryloxy-3-five-membered heteroaryl propylamine compound, and crystal form and use thereof | TRPA1, TRPM7, TRPV1 | SLC6A4 299/4885SLC6A3 226/4885SLC6A2 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.