SCHEMBL29448264

SCHEMBL29448264

ClCCCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.50
HDAC2 Q92769 2/20 0.49
FDFT1 P37268 2/20 0.49
TAAR1 Q96RJ0 2/20 0.48
HDAC1 Q13547 1/20 0.47
KCNH2 Q12809 1/20 0.46
MAOB P27338 2/20 0.45
HTR2A P28223 1/20 0.45
HSD11B1 P28845 2/20 0.44
MMP12 P39900 1/20 0.44
ABCC4 O15439 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.43
HTT P42858 1/20 0.43
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6610440 0.91 HDAC2 (0.53) FFAR1HDAC2FDFT1TAAR1HDAC1
SCHEMBL9553378 0.91 MAOB (0.43) HDAC2MAOBTSHR
SCHEMBL28644662 0.89 KCNH2 (0.42) FFAR1HDAC2FDFT1TAAR1HDAC1
SCHEMBL1939987 0.86 FFAR1 (0.54) FFAR1HDAC2FDFT1TAAR1KCNH2
SCHEMBL30869989 0.85 HDAC2 (0.60) FFAR1HDAC2FDFT1TAAR1HDAC1
SCHEMBL432616 0.85 SIGMAR1 (0.54) HDAC2HDAC1MAOBHTR2AIDO1
SCHEMBL9553137 0.84 MAOB (0.39) MAOBTSHR
SCHEMBL1939698 0.84 FFAR1 (0.52) FFAR1HDAC2FDFT1TAAR1KCNH2
SCHEMBL9826765 0.83 HTR2A (0.62) FFAR1HDAC2FDFT1TAAR1HDAC1
SCHEMBL9553269 0.83 HRH3 (0.43) HDAC2HDAC1MAOBGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109749755-B Liquid crystal compound and composition for improving environmental adaptability of liquid crystal material 西安近代化学研究所 2022-03-15 CN disclosed