SCHEMBL432616

SCHEMBL432616

ClCCCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.54
MAOA P21397 1/20 0.54
MAOB P27338 2/20 0.52
HTR2A P28223 1/20 0.52
IDO1 P14902 1/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC1 Q13547 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1271432 0.92 MAOA (0.58) SIGMAR1MAOAMAOBHTR2AL3MBTL1
SCHEMBL28879064 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL4306865 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL1006673 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL3694249 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL11254111 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL6680431 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL11033070 0.90 MAOA (0.56) SIGMAR1MAOAMAOBHTR2AL3MBTL1
SCHEMBL6678927 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL2582965 0.90 SIGMAR1 (0.58) SIGMAR1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 690 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509426-B1 Carbon-14 radioisotope-labeled flonicamid and synthesis method thereof Zhejiang Isotope Labelled Compounds Co., Ltd (CN) 2025-12-30 US claimed
CN-119285540-B Radioisotope carbon-14 labeled flonicamid and synthesis method thereof 浙江爱索拓标记医药科技有限公司 2025-04-04 CN claimed
CN-119285540-A Radioisotope carbon-14 labeled flonicamid and synthesis method thereof 浙江爱索拓标记医药科技有限公司 2025-01-10 CN claimed
US-20240209252-A1 METHODS FOR STABILIZING WATER SENSITIVE CLAYS AND MIGRATING FINES IN SUBTERRANEAN FORMATIONS PFP TECHNOLOGY, LLC (US) 2024-06-27 US claimed
CN-116478621-B Preparation method of water-oil amphoteric coating based on polyurethane-acrylic resin with active carbon nano tube as cross-linked structure 扬州市祥华新材料科技有限公司 2024-06-21 CN claimed
CN-117511387-B Preparation method of printing gloss oil containing poly (urethane-acrylate) 江苏众立生包装科技有限公司 2024-04-30 CN claimed
CN-117779469-A Construction method of host and guest of photodynamic/quaternary ammonium salt/boric acid antibacterial composite PET fiber coating 浙江豪欣纺织有限公司 2024-03-29 CN claimed
CN-117511387-A Preparation method of printing gloss oil containing poly (urethane-acrylate) 江苏众立生包装科技有限公司 2024-02-06 CN claimed
CN-117089054-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-11-21 CN claimed
US-11708523-B2 Methods for stabilizing water sensitive clays and migrating fines in subterranean formations PfP Industries LLC (US) 2023-07-25 US claimed
US-6482952-B2 ONE-STEP REACTION OF A CARBOXYLIC ACID HALIDE, A 1,2-AMINOALCOHOL, AND 2-ALKOXYPROPENE OR 2,2-DIALKOXYPROPANE IN AN ETHER SOLVENT AND IN THE PRESENCE OF LIOH MERCK & CO., INC. 2002-11-19 US claimed
US-20020132837-A1 Process for preparing acetonides MERCK SHARP & DOHME CORP. 2002-09-19 US claimed
EP-0848693-A4 ISOMERIZATION OF BISPHENOLS DOW CHEMICAL CO (US) 1999-03-17 EP claimed
CN-1200105-A Isomerization of bisphenols DOW CHEMICAL CO (US) 1998-11-25 CN claimed
EP-0848693-A1 ISOMERIZATION OF BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1998-06-24 EP claimed
WO-1997008122-A1 ISOMERIZATION OF BISPHENOLS THE DOW CHEMICAL COMPANY (US) 1997-03-06 WO claimed
CN-1137788-A Process for making polyphenols from ketones or aldehydes and phenols DOW CHEMICAL CO (US) 1996-12-11 CN claimed
EP-0725771-A1 PROCESS FOR MAKING POLYPHENOLS FROM KETONES OR ALDEHYDES AND PHENOLS THE DOW CHEMICAL COMPANY (US) 1996-08-14 EP claimed
WO-1996006819-A1 PROCESS FOR MAKING POLYPHENOLS FROM KETONES OR ALDEHYDES AND PHENOLS THE DOW CHEMICAL COMPANY (US) 1996-03-07 WO claimed
US-4039793-A PRODUCTION OF MONOCHLORO- AND ARYL SUBSTITUTED SATURATED COMPOUNDS UOP INC. (US) 1977-08-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509426-B1 Carbon-14 radioisotope-labeled flonicamid and synthesis method thereof TMEM14C, RPL14, FOS SIGMAR1 2227/4885MAOA 3633/4885MAOB 3151/4885
US-11708523-B2 Methods for stabilizing water sensitive clays and migrating fines in subterranean formations TLN1, DCX, VIM SIGMAR1 3499/4885MAOA 3867/4885MAOB 4620/4885
US-20240209252-A1 METHODS FOR STABILIZING WATER SENSITIVE CLAYS AND MIGRATING FINES IN SUBTERRANEAN FORMATIONS TLN1, DCX, VIM SIGMAR1 3499/4885MAOA 3867/4885MAOB 4620/4885
US-20020132837-A1 Process for preparing acetonides HSD11B1, HSD11B2, HACL2 SIGMAR1 3468/4885MAOA 2692/4885MAOB 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.