Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30856840 | 0.75 | EPAS1 (0.56) | — | |
| SCHEMBL16555485 | 0.75 | EPAS1 (0.56) | — | |
| SCHEMBL29155750 | 0.74 | ALDH1A1 (0.40) | NPY1RKMT2ACA2CA1CA9 | |
| SCHEMBL22588264 | 0.73 | ALDH1A1 (0.53) | RAB9AKMT2ASMN1; SMN2TBXA2RPTGS2 | |
| SCHEMBL29449330 | 0.72 | MERTK (0.47) | SMN1; SMN2TBXA2RCA2CA1CA9 | |
| SCHEMBL28720565 | 0.72 | MERTK (0.47) | SMN1; SMN2TBXA2RCA2CA1CA9 | |
| SCHEMBL23175141 | 0.71 | ALDH1A1 (0.62) | NPY1RKMT2ASMN1; SMN2CA2CA1 | |
| SCHEMBL10817391 | 0.70 | L3MBTL1 (0.59) | NPC1RAB9AKMT2ASMN1; SMN2CA2 | |
| SCHEMBL16376159 | 0.70 | TBXA2R (0.52) | NPC1RAB9AKMT2ASMN1; SMN2TBXA2R | |
| SCHEMBL31286145 | 0.70 | CA2 (0.46) | KMT2ACA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961005-B | Phenyl uracil compound and application thereof | 南北兄弟药业投资有限公司 | 2022-04-12 | — | — | CN | disclosed |