SCHEMBL29449786

SCHEMBL29449786

Brc1ccc(-c2ccc3cnccc3c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.59
CYP11B2 P19099 5/20 0.59
PRKCZ Q05513 1/20 0.58
CYP19A1 P11511 4/20 0.46
CYP17A1 P05093 3/20 0.46
TDO2 P48775 1/20 0.45
PIM1 P11309 2/20 0.44
CCNT1 O60563 1/20 0.44
CDK9 P50750 1/20 0.44
HASPIN Q8TF76 1/20 0.44
FASN P49327 1/20 0.43
AR P10275 1/20 0.43
AKT1 P31749 3/20 0.41
ALOX15 P16050 2/20 0.40
ROCK1 Q13464 2/20 0.40
DYRK3 O43781 1/20 0.40
ROCK2 O75116 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
CDK1 P06493 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28933997 1.00 CYP11B1 (0.59) CYP11B1CYP11B2PRKCZCYP19A1CYP17A1
SCHEMBL444504 0.86 PRKCZ (0.63) CYP11B1CYP11B2PRKCZCYP19A1CYP17A1
SCHEMBL6833606 0.84 CYP11B1 (0.54) CYP11B1CYP11B2PRKCZCYP19A1CYP17A1
SCHEMBL484716 0.84 CYP11B1 (0.56) CYP11B1CYP11B2PRKCZCYP19A1PIM1
SCHEMBL29547785 0.84 CYP11B1 (0.56) CYP11B1CYP11B2PRKCZCYP19A1PIM1
SCHEMBL6355545 0.82 CYP11B2 (0.61) CYP11B1CYP11B2PRKCZCYP19A1CYP17A1
Water SCHEMBL28177305 0.82 CYP11B1 (0.55) CYP11B1CYP11B2PRKCZCYP19A1PIM1
Ammonia Solution, Strong SCHEMBL27725592 0.82 CYP11B1 (0.55) CYP11B1CYP11B2PRKCZCYP19A1PIM1
Biphenyl SCHEMBL27880420 0.81 CYP11B1 (0.60) CYP11B1CYP11B2PRKCZCYP19A1CYP17A1
SCHEMBL13098708 0.81 ALDH1A1 (0.52) CYP11B1CYP11B2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181146-A Novel compound for capping layer and organic light-emitting element including same 东进世美肯株式会社 2022-03-15 CN disclosed