Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.38 |
| ▸ | NRP1 | O14786 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31214578 | 0.92 | ACE (0.45) | ACEOPRM1OPRK1 | |
| SCHEMBL30272488 | 0.91 | ACE (0.40) | ACEEPHA2F2RRENNRP1 | |
| SCHEMBL30866232 | 0.91 | ACE (0.44) | ACEEPHA2RENNRP1OPRM1 | |
| SCHEMBL31064903 | 0.91 | NTSR1 (0.43) | EPHA2 | |
| SCHEMBL9616909 | 0.89 | OPRK1 (0.43) | ACERENOPRM1OPRK1 | |
| SCHEMBL30552516 | 0.89 | ACE (0.49) | ACENRP1OPRM1OPRK1 | |
| SCHEMBL11644393 | 0.89 | OPRK1 (0.43) | ACERENOPRM1OPRK1 | |
| SCHEMBL9616907 | 0.89 | OPRK1 (0.43) | ACERENOPRM1OPRK1 | |
| SCHEMBL29369248 | 0.89 | ACE (0.42) | ACERENNRP1OPRM1OPRK1 | |
| SCHEMBL31257058 | 0.89 | PLK1 (0.40) | ACEOPRM1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117582485-B | Application of Sipunculus nudus tripeptide in preparation of osteoporosis drugs | 湛江中心人民医院 | 2024-06-07 | — | — | CN | claimed |
| CN-117582485-A | Application of Sipunculus nudus tripeptide in preparation of osteoporosis drugs | 湛江中心人民医院 | 2024-02-23 | — | — | CN | claimed |
| CN-114315959-B | Sipunculus nudus tripeptide, sipunculus nudus tripeptide metal chelate and application thereof | 广东湛江海洋医药研究院 | 2023-09-29 | — | — | CN | claimed |
| CN-113940961-B | Traditional Chinese medicine extract, composition and application thereof in preparation of toothpaste or mouthwash with tooth cleaning and solidifying effects | 广东湛江海洋医药研究院 | 2022-09-30 | — | — | CN | claimed |
| WO-2022156190-A1 | ANTIHYPERTENSIVE PEPTIDE, LONG-ACTING ANTIHYPERTENSIVE PEPTIDE, AND PREPARATION METHODS THEREFOR | 南方海洋科学与工程广东省实验室(湛江) | 2022-07-28 | — | — | WO | claimed |
| CN-114315959-A | Sipunculus nudus tripeptide, Sipunculus nudus tripeptide metal chelate and application thereof | 广东湛江海洋医药研究院 | 2022-04-12 | — | — | CN | claimed |
| CN-117582485-B | Application of Sipunculus nudus tripeptide in preparation of osteoporosis drugs | 湛江中心人民医院 | 2024-06-07 | — | — | CN | disclosed |
| CN-117582485-B | Application of Sipunculus nudus tripeptide in preparation of osteoporosis drugs | 湛江中心人民医院 | 2024-06-07 | — | — | CN | disclosed |
| CN-117582485-A | Application of Sipunculus nudus tripeptide in preparation of osteoporosis drugs | 湛江中心人民医院 | 2024-02-23 | — | — | CN | disclosed |
| CN-117582485-A | Application of Sipunculus nudus tripeptide in preparation of osteoporosis drugs | 湛江中心人民医院 | 2024-02-23 | — | — | CN | disclosed |
| CN-114315959-B | Sipunculus nudus tripeptide, sipunculus nudus tripeptide metal chelate and application thereof | 广东湛江海洋医药研究院 | 2023-09-29 | — | — | CN | disclosed |
| CN-114315959-B | Sipunculus nudus tripeptide, sipunculus nudus tripeptide metal chelate and application thereof | 广东湛江海洋医药研究院 | 2023-09-29 | — | — | CN | disclosed |
| CN-114209636-B | Composition and application thereof in preparing daily chemical products with hair growth and/or hair blacking effects | 广东湛江海洋医药研究院 | 2023-05-12 | — | — | CN | disclosed |
| CN-112661811-B | Antihypertensive peptide, long-acting antihypertensive peptide and preparation method thereof | 南方海洋科学与工程广东省实验室(湛江) | 2022-10-21 | — | — | CN | disclosed |
| CN-113940961-B | Traditional Chinese medicine extract, composition and application thereof in preparation of toothpaste or mouthwash with tooth cleaning and solidifying effects | 广东湛江海洋医药研究院 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022156190-A1 | ANTIHYPERTENSIVE PEPTIDE, LONG-ACTING ANTIHYPERTENSIVE PEPTIDE, AND PREPARATION METHODS THEREFOR | 南方海洋科学与工程广东省实验室(湛江) | 2022-07-28 | — | — | WO | disclosed |
| CN-114315959-A | Sipunculus nudus tripeptide, Sipunculus nudus tripeptide metal chelate and application thereof | 广东湛江海洋医药研究院 | 2022-04-12 | — | — | CN | disclosed |
| CN-114315959-A | Sipunculus nudus tripeptide, Sipunculus nudus tripeptide metal chelate and application thereof | 广东湛江海洋医药研究院 | 2022-04-12 | — | — | CN | disclosed |
| CN-114209636-A | Composition and application thereof in preparation of daily chemical products with hair growing and/or hair blacking effects | 广东湛江海洋医药研究院 | 2022-03-22 | — | — | CN | disclosed |