Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | NRP1 | O14786 | 2/20 | 0.45 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422984 | 0.98 | ACE (0.47) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL30672574 | 0.96 | ACE (0.46) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL5507610 | 0.96 | NRP1 (0.48) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL5507620 | 0.96 | NRP1 (0.48) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL29802045 | 0.95 | OPRK1 (0.49) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL29721451 | 0.95 | ACE (0.45) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL30909415 | 0.94 | ACE (0.44) | ACENRP1OPRK1OPRM1 | |
| SCHEMBL29721101 | 0.93 | ACE (0.45) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL6362164 | 0.92 | NRP1 (0.45) | ACENRP1NTSR2NTSR1OPRK1 | |
| SCHEMBL31214578 | 0.91 | ACE (0.45) | ACEOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188139-A1 | VEGF-C MUTEINS FOR SELECTIVE LYMPHATIC STIMULATION | YALE UNIVERSITY (US) | 2025-06-12 | — | — | US | disclosed |
| CN-119522235-A | VEGF-C muteins for selective lymphatic stimulation | 耶鲁大学 | 2025-02-25 | — | — | CN | disclosed |
| EP-4490175-A2 | VEGF-C MUTEINS FOR SELECTIVE LYMPHATIC STIMULATION | Yale University (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2024168252-A2 | USE OF INHIBITORS OF VEGF-C SIGNALING FOR INHIBITING IMMUNE RESPONSES AND INCREASING GENE THERAPY EFFICACY | YALE UNIVERSITY (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2023172964-A2 | VEGF-C MUTEINS FOR SELECTIVE LYMPHATIC STIMULATION | YALE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |